avaSetFiltered_annot: AVASet variant annotations

In R453Plus1Toolbox: A package for importing and analyzing data from Roche's Genome Sequencer System

Description

These are example annotations for 4 variants of an AVASet (try data(avaSetFiltered) to retrieve the corresponding link{AVASet-class} object). The annotations include affected genes, exons and codons as well as resulting amino acid changes and dbSNP identifiers (if the mutation is already known).

Usage

data(avaSetFiltered_annot)

Format

Formal class 'AnnotatedVariants'

Source

‘Next-generation sequencing technology reveals a characteristic pattern of molecular mutations in 72.8% of chronic myelomonocytic leukemia by detecting frequent alterations in TET2, CBL, RAS, and RUNX1’ (Kohlmann A et al., J Clin Oncol. 2010 Aug 20;28(24):3858-65. Epub 2010 Jul 19)

Examples

    data(avaSetFiltered_annot)

R453Plus1Toolbox documentation built on Nov. 8, 2020, 5:59 p.m.