Description Usage Arguments Value See Also Examples
Show the details of a human DHS filter
1 2 | ## S4 method for signature 'HumanDHSFilter'
show(object)
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object |
An object of class HumanDHSFilter |
A list, where one element a character vector of transcription factors that match the GO term and the other is an empty data frame.
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 | ## Not run:
# Make a filter and show it
# load(system.file(package="trena", "extdata/ampAD.154genes.mef2cTFs.278samples.RData"))
targetGene <- "VRK2"
promoter.length <- 1000
genomeName <- "hg38"
db.address <- system.file(package="trena", "extdata")
genome.db.uri <- paste("sqlite:/", db.address, "vrk2.neighborhood.hg38.gtfAnnotation.db", sep = "/")
jaspar.human <- as.list(query(query(MotifDb, "sapiens"),"jaspar2016"))
# Grab regions for VRK2 using shoulder size of 1000
trena <- Trena(genomeName)
tbl.regions <- getProximalPromoter(trena, "VRK2", 1000, 1000)
hd.filter <- HumanDHSFilter(genomeName, pwmMatchPercentageThreshold = 85,
geneInfoDatabase.uri = genome.db.uri, regions = tbl.regions, pfms = jaspar.human)
show(hd.filter)
## End(Not run)
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