Detection of biases in the usage of immunoglobulin (Ig) genes is an important task in immune repertoire profiling. IgGeneUsage detects aberrant Ig gene usage between biological conditions using a probabilistic model which is analyzed computationally by Bayes inference. With this IgGeneUsage also avoids some common problems related to the current practice of null-hypothesis significance testing.
Package details |
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Bioconductor views | Bayesian BiomedicalInformatics DifferentialExpression Genetics ImmunoOncology MathematicalBiology Regression |
Maintainer | |
License | MIT + file LICENSE |
Version | 1.17.27 |
URL | https://github.com/snaketron/IgGeneUsage |
Package repository | View on GitHub |
Installation |
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