preprocess: Preprocess the SingleCellExperiment

In Wancen/airpart: Differential cell-type-specific allelic imbalance

Preprocess the SingleCellExperiment

Description

Preprocess the SingleCellExperiment

Usage

preprocess(sce, pc = 2)

Arguments

sce	SingleCellExperiment with a1 (effect allele) and a2 (non-effect allele). The allelic ratio will be calculated as a1 / (a1 + a2).
pc	pseudocount for calculating the smoothed ratio

Value

SingleCellExperiment with total count, allelic ratio = a1/(a1 + a2), and pseud-ocount-smoothed ratio

Examples

library(SummarizedExperiment)
sce <- makeSimulatedData()
sce <- preprocess(sce)
assayNames(sce)

Wancen/airpart documentation built on March 12, 2023, 11:53 a.m.