panobinostat_2DTPP_data: 2D-TPP-CCR example dataset
In DoroChilds/TPP: Analyze thermal proteome profiling (TPP) experiments

Example subset of a Panobinostat 2D-TPP dataset

A list with two subsets of a dataset obtained by 2D-TPP experiments to investigate drug effects for HDAC inhibitor Panobinostat. The experiment was performed on living HepG2 cells (see Becher et al. (2016). Thermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat. Nature Chemical Biology, (September)) It contains 7 HDACs as well as a random selection of 493 further proteins.

You can use this dataset to explore the TPP package functionalities without invoking the whole time consuming analysis on the big dataset.

panobinostat_2DTPP_config, panobinostat_2DTPP_smallExample

DoroChilds/TPP documentation built on Oct. 31, 2021, 4:38 a.m.