microbiome-goodrich: Microbiome, Goodrich dataset results

In stephaniehicks/benchmarkfdrData2019: Data and Benchmarking Results from Korthauer and Kimes et al. (2019)

Microbiome, Goodrich dataset results

Description

Results for case study on 16S microbiome differential testing of Goodrich et al. (2014) dataset described in Korthauer and Kimes et al. (2019). Wilcoxon rank-sum test was used to test for differential abundance between samples from lean (body mass index, BMI < 25) and obsese (BMI > 30) individuals.

Arguments

metadata

logical whether to load metadata (TRUE) or full resource (FALSE). (default = FALSE)

Details

Results for this case study include:

• goodrich-genus-benchmark: testing at genus-level using ubiquity as covariate.

• goodrich-genus-abun-benchmark: testing at genus-level using mean abundance as covariate.

• goodrich-genus-uninf-benchmark: testing at genus-level using uninformative covariate.

• goodrich-otus-benchmark: testing at OTU-level using ubiquity as covariate.

References

• Goodrich, J. K. et al. (2014). Human genetics shape the gut microbiome. Cell, 159(4), 789-799.

See Also

microbiome-schubert, microbiome-baxter, microbiome-papa, microbiome-enigma

Examples

`goodrich-genus-benchmark`(metadata = TRUE)

## Not run: 
`goodrich-genus-benchmark`()
`goodrich-genus-abun-benchmark`()
`goodrich-genus-uninf-benchmark`()
`goodrich-otus-benchmark`()

## End(Not run)

stephaniehicks/benchmarkfdrData2019 documentation built on April 13, 2025, 9:02 p.m.