dorothea_hs_pancancer: Human DoRothEA (pancancer)
In saezlab/dorothea: Collection Of Human And Mouse TF Regulons
dorothea_hs_pancancer R Documentation
Human DoRothEA (pancancer)
Description
A table reporting signed human TF-target interactions for cancer application.
The difference to "dorothea_hs" is that TGCA gene expression data was used
instead of GTEx to infer the networks with ARACNE. This database covers
in total 1344 TFs targeting 20,582 genes with 213,230 unique interactions.
In addition, each TF is accompanied with an empirical confidence level that
was derived from the number of supporting evidences for this
TF/interaction. The range is from A (high quality) to E (low quality).
Format
A table of human TF-target interactions:
- tf
TF identifier as HGNC symbols
- confidence
Summary confidence score classifying regulons based on
their quality
- target
target identifier as HGNC symbols
- mor
mode of regulation indicating the effect of a TF on the
target
Source
saezlab/dorothea documentation built on Feb. 24, 2024, 8:12 p.m.
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| dorothea_hs_pancancer | R Documentation |
Human DoRothEA (pancancer)
Description
A table reporting signed human TF-target interactions for cancer application. The difference to "dorothea_hs" is that TGCA gene expression data was used instead of GTEx to infer the networks with ARACNE. This database covers in total 1344 TFs targeting 20,582 genes with 213,230 unique interactions. In addition, each TF is accompanied with an empirical confidence level that was derived from the number of supporting evidences for this TF/interaction. The range is from A (high quality) to E (low quality).
Format
A table of human TF-target interactions:
- tf
TF identifier as HGNC symbols
- confidence
Summary confidence score classifying regulons based on their quality
- target
target identifier as HGNC symbols
- mor
mode of regulation indicating the effect of a TF on the target
Source
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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