cr_add_subtype_specificity: Add subtype specificity columns in cr

Description Usage Arguments Details Value Author(s) Examples

Description

Add subtype specificity columns in cr

Usage

1
cr_add_subtype_specificity(cr, cutoff = 0.05, suffix = "_ss")

Arguments

cr

correlated regions generated by filter_correlated_regions or reduce_cr

cutoff

cutoff for p-values of ANOVA test

suffix

suffix of column names

Details

If factor is set in correlated_regions, this function can assign subtype specificity to each subtype.

We use following digits to represent subtype specificity: 1 is defined as the methylation is higher than all other subtypes and the difference is significant. -1 is defined as the methylation is lower than all other subtypes and the difference is significant. All the others are defined as 0.

Value

A GRanges object

Author(s)

Zuguang Gu <z.gu@dkfz.de>

Examples

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# There is no example
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eilslabs/epic documentation built on May 16, 2019, 1:24 a.m.