UMI-4C is a technique that allows characterization of 3D chromatin interactions with a bait of interest, taking advantage of a sonication step to produce unique molecular identifiers (UMIs) that help remove duplication bias, thus allowing a better differential comparsion of chromatin interactions between conditions. This package allows processing of UMI-4C data, starting from FastQ files provided by the sequencing facility. It provides two statistical methods for detecting differential contacts and includes a visualization function to plot integrated information from a UMI-4C assay.
Package details |
|
---|---|
Bioconductor views | Alignment Coverage Normalization Preprocessing QualityControl Sequencing Visualization |
Maintainer | |
License | Artistic-2.0 |
Version | 1.13.0 |
URL | https://github.com/Pasquali-lab/UMI4Cats |
Package repository | View on GitHub |
Installation |
Install the latest version of this package by entering the following in R:
|
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.