Description Usage Arguments Value Examples
Get intervals of flux variability (FVA) from an observed growth rate
1 2 3 | get_fva_intervals_from_observations(model, observed_growth_rate,
metabolites_rates = NULL,
biomass_flux_index = get_biomass_flux_position(model))
|
model |
a genome-scale metabolic model of class modelorg |
observed_growth_rate |
a numerical value for the observed growth rate |
metabolites_rates |
Optional. a data.frame consisting of the name of the metabolites, their concentrations and rates in mmol/gDW/h to adjust the model uptake rates. The column name must be "name", "concentrations","rates" |
biomass_flux_index |
Optional. Index of the biomass flux as returned by
|
Return the interval of fluxes values compatible with the observed growth rate through flux variability analysis
1 2 3 4 5 6 | data("iMM904")
metabolites_rates<-data.frame(name=c("D-Glucose","Glycerol"),
concentrations=c(16,0),rates=c(-2.81,-8.01))
FluxesVarFromObs<-get_fva_intervals_from_observations(iMM904,0.205,
metabolites_rates=metabolites_rates)
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