batchQC_analyze: Checks for presence of batch effect and reports whether the...

Description Usage Arguments Value Examples

View source: R/batchQC.R

Description

Checks for presence of batch effect and reports whether the batch needs to be adjusted

Usage

1

Arguments

data.matrix

Given data or simulated data from rnaseq_sim()

batch

Batch covariate

mod

Model matrix for outcome of interest and other covariates besides batch

Value

pca Principal Components Analysis object of the data

Examples

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11
nbatch <- 3
ncond <- 2
npercond <- 10
data.matrix <- rnaseq_sim(ngenes=50, nbatch=nbatch, ncond=ncond, npercond=
    npercond, basemean=10000, ggstep=50, bbstep=2000, ccstep=800, 
    basedisp=100, bdispstep=-10, swvar=1000, seed=1234)
batch <- rep(1:nbatch, each=ncond*npercond)
condition <- rep(rep(1:ncond, each=npercond), nbatch)
pdata <- data.frame(batch, condition)
modmatrix = model.matrix(~as.factor(condition), data=pdata)
batchQC_analyze(data.matrix, batch, mod=modmatrix)

Example output

sh: 1: cannot create /dev/null: Permission denied

Call:
lm(formula = pc[, 1] ~ fbatch + fcond)

Residuals:
     Min       1Q   Median       3Q      Max 
-1.95358 -0.45328  0.04717  0.60252  1.57878 

Coefficients:
            Estimate Std. Error t value Pr(>|t|)    
(Intercept)  -7.4258     0.2051  -36.20   <2e-16 ***
fbatch2       5.9121     0.2512   23.53   <2e-16 ***
fbatch3      12.5239     0.2512   49.85   <2e-16 ***
fcond1        2.5608     0.2051   12.48   <2e-16 ***
---
Signif. codes:  0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1

Residual standard error: 0.7945 on 56 degrees of freedom
Multiple R-squared:  0.9793,	Adjusted R-squared:  0.9781 
F-statistic: 881.1 on 3 and 56 DF,  p-value: < 2.2e-16


Call:
lm(formula = pc[, 2] ~ fbatch + fcond)

Residuals:
    Min      1Q  Median      3Q     Max 
-3.7975 -0.6522  0.1296  0.7709  2.8918 

Coefficients:
            Estimate Std. Error t value Pr(>|t|)
(Intercept)  0.09594    0.32455   0.296    0.769
fbatch2     -0.43845    0.39749  -1.103    0.275
fbatch3     -0.07704    0.39749  -0.194    0.847
fcond1       0.15179    0.32455   0.468    0.642

Residual standard error: 1.257 on 56 degrees of freedom
Multiple R-squared:  0.02788,	Adjusted R-squared:  -0.0242 
F-statistic: 0.5354 on 3 and 56 DF,  p-value: 0.66


Call:
lm(formula = pc[, 3] ~ fbatch + fcond)

Residuals:
    Min      1Q  Median      3Q     Max 
-4.6201 -0.6683  0.2035  0.6785  2.6077 

Coefficients:
             Estimate Std. Error t value Pr(>|t|)   
(Intercept)  0.339994   0.300463   1.132  0.26264   
fbatch2     -0.001188   0.367990  -0.003  0.99744   
fbatch3      0.195881   0.367990   0.532  0.59663   
fcond1      -0.809783   0.300463  -2.695  0.00927 **
---
Signif. codes:  0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1

Residual standard error: 1.164 on 56 degrees of freedom
Multiple R-squared:  0.1201,	Adjusted R-squared:  0.07296 
F-statistic: 2.548 on 3 and 56 DF,  p-value: 0.06497


Call:
lm(formula = pc[, 4] ~ fbatch + fcond)

Residuals:
    Min      1Q  Median      3Q     Max 
-3.3476 -0.7101 -0.0702  0.6425  2.4201 

Coefficients:
            Estimate Std. Error t value Pr(>|t|)
(Intercept) -0.23142    0.29813  -0.776    0.441
fbatch2      0.39746    0.36513   1.089    0.281
fbatch3     -0.04282    0.36513  -0.117    0.907
fcond1       0.22641    0.29813   0.759    0.451

Residual standard error: 1.155 on 56 degrees of freedom
Multiple R-squared:  0.04019,	Adjusted R-squared:  -0.01122 
F-statistic: 0.7817 on 3 and 56 DF,  p-value: 0.5091


Call:
lm(formula = pc[, 5] ~ fbatch + fcond)

Residuals:
    Min      1Q  Median      3Q     Max 
-2.6261 -0.7063  0.0244  0.7560  2.1307 

Coefficients:
            Estimate Std. Error t value Pr(>|t|)  
(Intercept)  -0.1117     0.2764  -0.404   0.6877  
fbatch2      -0.2357     0.3385  -0.696   0.4891  
fbatch3      -0.1891     0.3385  -0.559   0.5787  
fcond1        0.5066     0.2764   1.833   0.0721 .
---
Signif. codes:  0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1

Residual standard error: 1.071 on 56 degrees of freedom
Multiple R-squared:  0.06516,	Adjusted R-squared:  0.01508 
F-statistic: 1.301 on 3 and 56 DF,  p-value: 0.2831

Standard deviations (1, .., p=50):
 [1] 5.37385516 1.24203430 1.20861596 1.14822039 1.07868428 1.04344750
 [7] 0.98556583 0.97947654 0.92174077 0.91320945 0.89449780 0.86149785
[13] 0.84706775 0.82180281 0.78228239 0.76482753 0.74616903 0.72621231
[19] 0.68668468 0.67677100 0.65945857 0.63172156 0.62143893 0.57437768
[25] 0.55426563 0.54913491 0.51748897 0.50242423 0.49012697 0.47951732
[31] 0.46361561 0.42724253 0.41669333 0.38607166 0.36938047 0.34214576
[37] 0.31700973 0.29762569 0.28727510 0.28553312 0.25856150 0.24807391
[43] 0.21978999 0.17624031 0.16927586 0.15770845 0.14164507 0.11290626
[49] 0.10481578 0.07966933

Rotation (n x k) = (50 x 50):
            PC1          PC2         PC3          PC4          PC5
 [1,] 0.1428409  0.093906004 -0.09708496  0.098095278 -0.138884700
 [2,] 0.1432312 -0.052758087  0.10416026 -0.014042349  0.049685604
 [3,] 0.1365965  0.165763489 -0.16000022  0.098825776 -0.028820049
 [4,] 0.1469878 -0.219091929 -0.04951724 -0.049684634 -0.047872749
 [5,] 0.1432096 -0.047711504 -0.14473273  0.099669617  0.240824830
 [6,] 0.1491981  0.070114109  0.01425394  0.079000459 -0.080750203
 [7,] 0.1429338  0.132072602 -0.13705556 -0.050849739 -0.268729888
 [8,] 0.1413007  0.069892777 -0.13885508 -0.108566261  0.264297425
 [9,] 0.1463438  0.114626327 -0.26323460  0.008684241 -0.018485553
[10,] 0.1422389 -0.115896459  0.16688856  0.232385695 -0.143539494
[11,] 0.1372982  0.052880496 -0.07533488 -0.245358373 -0.207851109
[12,] 0.1379562  0.281255568 -0.04395646  0.144068813 -0.138330061
[13,] 0.1562253  0.119421687  0.07530289 -0.001775128 -0.016220709
[14,] 0.1361448 -0.135401686  0.20449879  0.158073402  0.187053235
[15,] 0.1454618 -0.248680002  0.16810132  0.036362378  0.017525777
[16,] 0.1494762 -0.107087833 -0.05799968 -0.155035063  0.027386310
[17,] 0.1451022  0.007961209 -0.18004497  0.005023514  0.051043323
[18,] 0.1282341  0.067293859  0.18149589  0.133104571 -0.229307603
[19,] 0.1418664  0.096316720  0.12728688 -0.014562895 -0.060107723
[20,] 0.1435351  0.189613624  0.02165129  0.152963057  0.168530308
[21,] 0.1556216 -0.099733483 -0.02627934  0.095822646  0.070996725
[22,] 0.1421520 -0.060135279 -0.17786720 -0.009941430 -0.166750425
[23,] 0.1368131 -0.168287016 -0.15896895  0.135336377 -0.141469857
[24,] 0.1454848  0.054482141  0.03939914  0.007426360  0.033462094
[25,] 0.1430666 -0.215989251  0.05196058  0.008788797 -0.112062597
[26,] 0.1407790  0.060908760  0.08991103 -0.184375825  0.074989542
[27,] 0.1514542  0.064435824  0.11010495 -0.128734611 -0.006757529
[28,] 0.1507267 -0.011617560  0.03129210  0.142512895 -0.127936950
[29,] 0.1471663 -0.212554490  0.14865359 -0.172602057  0.081994068
[30,] 0.1471254  0.146392440 -0.09911845 -0.132005666  0.034106696
[31,] 0.1355319 -0.157483834  0.12896004 -0.174241666 -0.130450890
[32,] 0.1434191 -0.010340115 -0.09677506 -0.094957364  0.014614964
[33,] 0.1458222  0.111118905  0.08458383 -0.016327089  0.085994647
[34,] 0.1417662  0.086506607  0.11232353  0.097662109 -0.387748104
[35,] 0.1447757 -0.252323247  0.12837721  0.188582955  0.071448301
[36,] 0.1397404  0.075581682 -0.02735131 -0.114777168  0.331256033
[37,] 0.1467416  0.214076244  0.04413713  0.092506613  0.209168072
[38,] 0.1288961 -0.303234776 -0.27240707 -0.065597009  0.089669429
[39,] 0.1333704  0.055220390 -0.16339313  0.246453943 -0.056409530
[40,] 0.1277452 -0.018300443  0.19110456 -0.049596150  0.026956740
[41,] 0.1261049  0.170624260  0.21726570  0.002551940 -0.079841560
[42,] 0.1335246 -0.002956071  0.24980722  0.241166323  0.199570562
[43,] 0.1449802  0.005032074 -0.04969729 -0.109199793 -0.016729685
[44,] 0.1333428 -0.269422953  0.01371882 -0.211486353 -0.156053862
[45,] 0.1323319 -0.213015485 -0.17435643  0.268533572  0.118758829
[46,] 0.1408328  0.035752536 -0.27653977  0.014759087  0.094089757
[47,] 0.1477849  0.070302812 -0.15680312  0.000778323  0.008954019
[48,] 0.1317724  0.143787614  0.13147013 -0.240469883  0.092266259
[49,] 0.1330103 -0.002890743  0.01845944 -0.389578225 -0.031174549
[50,] 0.1344629  0.154246751  0.21882797 -0.064156759  0.128102550
                PC6         PC7         PC8          PC9         PC10
 [1,]  1.057742e-01 -0.23538711  0.08386086 -0.042490448  0.106228703
 [2,]  2.127898e-01  0.02892399 -0.07926812 -0.250263525  0.128446951
 [3,]  2.915453e-01  0.23986862  0.01281772  0.241629294 -0.086788332
 [4,] -8.877456e-03  0.06829730  0.19116250  0.266930310 -0.171680549
 [5,]  7.478338e-02 -0.26904163 -0.13087882 -0.040797907 -0.004268275
 [6,]  4.594550e-02 -0.00674125  0.16469339  0.099466542  0.023100654
 [7,] -3.844750e-02 -0.17287273 -0.06680536 -0.019570467  0.202173661
 [8,] -1.061109e-01  0.08911107  0.16578011  0.069245467 -0.055583334
 [9,]  9.192449e-02  0.03184259  0.02780395  0.034390274  0.091813904
[10,]  8.516620e-02 -0.07790053 -0.28680431 -0.051243173 -0.126625608
[11,] -6.885604e-02 -0.10085691  0.14607128 -0.306814459  0.004118581
[12,] -1.347301e-02  0.10634248 -0.26411606 -0.031665758 -0.187959973
[13,] -2.065483e-01 -0.07175860 -0.06654491  0.030032905  0.061641044
[14,]  1.139226e-01 -0.01508137  0.09877166  0.239035719  0.085366149
[15,]  3.732541e-02 -0.05038467  0.10585356  0.101664049 -0.113483885
[16,]  2.064711e-02  0.19422998  0.10009077 -0.240337269  0.124151802
[17,] -2.489234e-01  0.15787775 -0.07613443  0.045882382 -0.013287985
[18,] -6.252651e-02  0.28965305 -0.26479355  0.134276256  0.067522482
[19,] -2.480382e-01  0.09791055 -0.11286878  0.032776989  0.198625081
[20,]  8.555796e-02 -0.04894219 -0.04787438 -0.104269659  0.189706624
[21,] -7.427736e-02 -0.03287849  0.23703666 -0.087858106 -0.161902588
[22,] -1.366387e-01 -0.08797062 -0.00150032 -0.009268987 -0.273208280
[23,]  1.156844e-01 -0.15023829  0.01017285 -0.088249286 -0.274122658
[24,]  1.887317e-01  0.09539473  0.16957954  0.027121172  0.301054245
[25,]  8.541816e-02  0.01305351 -0.14683465  0.254814297  0.039812151
[26,]  2.173556e-01  0.02062515  0.07578603  0.073635706  0.144239958
[27,] -9.440647e-02 -0.01892817 -0.09871189 -0.005641399  0.092442767
[28,] -9.183493e-05  0.06420247  0.09825811 -0.134786778  0.123207516
[29,] -1.487517e-01  0.04400108 -0.18710875 -0.053331849  0.173039351
[30,]  2.993303e-02 -0.16141993 -0.23577764  0.055983477 -0.036798606
[31,]  2.351830e-01 -0.21617188 -0.01983191  0.102927026 -0.029330750
[32,]  1.527496e-01  0.08609514 -0.16058057 -0.302782433 -0.026317495
[33,]  1.055833e-01  0.02958946  0.12841874 -0.085310656  0.126258415
[34,] -3.569113e-02 -0.01307430  0.16640043 -0.006521833 -0.082445301
[35,]  3.877703e-02 -0.07254960  0.15238727 -0.081458103  0.059246335
[36,] -6.812919e-02  0.03331068 -0.07354879  0.012493903 -0.139407213
[37,] -3.364137e-02 -0.06260033  0.18797769  0.031059751 -0.015924459
[38,] -2.283315e-01 -0.02056102 -0.13650870  0.059176147  0.045051991
[39,] -4.151309e-02  0.22920349  0.26342216 -0.110908262 -0.014999874
[40,] -2.519362e-01 -0.37118844 -0.00772624 -0.134642861  0.067441271
[41,] -3.579160e-01 -0.09643413  0.22688946  0.192797728 -0.035642121
[42,]  1.046422e-01  0.02813609 -0.12721625 -0.268383534 -0.238935158
[43,] -5.078433e-02  0.22231466 -0.02449162 -0.189289478 -0.061919470
[44,]  1.043704e-02  0.17861668  0.05556456  0.033439927  0.122353139
[45,] -2.339735e-01  0.19485836 -0.09112715 -0.022423759  0.045502871
[46,]  3.200647e-03 -0.21737615 -0.02807754  0.188034776  0.180365526
[47,]  1.392410e-01 -0.18910626 -0.11738840  0.186745558 -0.057392465
[48,] -3.346974e-02 -0.01360015  0.11936259 -0.075817863 -0.398787143
[49,]  1.789439e-01  0.14631769 -0.03384321  0.058552166 -0.168043756
[50,] -2.914245e-02  0.11187162 -0.13755855  0.209348365 -0.103254896
              PC11         PC12          PC13          PC14         PC15
 [1,] -0.001572544 -0.025974715  0.1028527090  0.3169193795 -0.220371867
 [2,]  0.014643830  0.043274223  0.0722104070 -0.3829889251 -0.166768453
 [3,] -0.199099361 -0.049204534  0.0822500485 -0.0386086957 -0.039800780
 [4,]  0.021603322 -0.080032463 -0.1472446124 -0.0405373909 -0.036373310
 [5,] -0.015850778  0.003971891 -0.0681253845 -0.1915098471  0.241337770
 [6,]  0.222641735 -0.007899558 -0.1489148348  0.1749101128  0.236709533
 [7,]  0.117247013 -0.089210452  0.0543867853  0.1833842482 -0.137319301
 [8,] -0.071671804  0.313580721  0.1135565313 -0.0070633887  0.092834995
 [9,]  0.160369038  0.303356345 -0.0028328523  0.1369204575 -0.048275771
[10,] -0.014256516  0.087717677  0.1308976338  0.1094219388 -0.068769016
[11,]  0.043986909  0.089164222  0.2367615932 -0.1986134162  0.041613226
[12,] -0.017374859 -0.129875698  0.0625206956 -0.0192922172  0.120335359
[13,] -0.008203427  0.162778489  0.0017158134 -0.0359413340 -0.120105043
[14,]  0.082426667 -0.089155072  0.3130974265 -0.1528451949 -0.005074339
[15,]  0.152831640  0.134518601 -0.0344526791  0.0255783119 -0.023442416
[16,] -0.110429020 -0.225027787  0.0182613560 -0.0286327553  0.090045988
[17,] -0.237917016 -0.032582814  0.2835440990  0.0391347922 -0.022352664
[18,]  0.167851224 -0.039418621 -0.0183441492 -0.1625123118  0.282661860
[19,] -0.219801350 -0.135327606 -0.2079683190 -0.0041655854  0.093654346
[20,]  0.056554416  0.098253275  0.1960658842  0.0275989511  0.131165578
[21,] -0.099094943 -0.186857501  0.0351263445  0.0627873355 -0.075657222
[22,]  0.081170897 -0.177309218 -0.0004306734 -0.1408558251 -0.255391879
[23,] -0.254809894 -0.087339937 -0.0871920914 -0.0056519045  0.091742482
[24,] -0.162326589  0.005461561 -0.2149585791  0.0641861884 -0.031553630
[25,] -0.086224482  0.191970488 -0.0314871801 -0.1342883312 -0.038332296
[26,] -0.008089449 -0.378796108 -0.0425453566  0.0365920766 -0.281025765
[27,]  0.384798803 -0.164401803  0.0446148983  0.0737688219 -0.038019601
[28,]  0.163514835  0.193272745  0.1982579990 -0.0007495177 -0.021009069
[29,] -0.078737959 -0.078188548 -0.0565589264  0.0108127341 -0.098782912
[30,] -0.079058730 -0.071328427 -0.2606803223 -0.0598080727 -0.002385048
[31,]  0.070285361 -0.067794005  0.0540622270  0.2566659061  0.350212381
[32,] -0.150899395 -0.001910786 -0.0157900396  0.1274311118 -0.007233154
[33,] -0.091260464 -0.094217689 -0.0174794962  0.0048745461  0.253423106
[34,]  0.020891902  0.106745421 -0.1405932804  0.0060755511 -0.053209651
[35,]  0.045444094 -0.042773903 -0.2009689758 -0.0043969283  0.009883379
[36,]  0.305287332 -0.204306826  0.1092495736  0.0848711852  0.086124225
[37,] -0.084847356  0.086948481 -0.0719572658  0.1764877744 -0.177140577
[38,]  0.146880744  0.074882842 -0.0518253681  0.1269040581  0.022266084
[39,]  0.050958264  0.041803354 -0.1189945153 -0.1854611727  0.143101651
[40,] -0.265727318  0.197137826 -0.0705886900 -0.0169971845  0.146584697
[41,] -0.153885089 -0.186102196  0.1241131592 -0.1019856951  0.067825301
[42,]  0.010242451  0.026182825 -0.0480929292  0.0235309705 -0.145524508
[43,]  0.182509144  0.038061946 -0.3599266531 -0.0797281607 -0.109261402
[44,] -0.061697972  0.115509597  0.2579300845 -0.0863525660 -0.122984110
[45,] -0.041593793 -0.083060492  0.0578308910  0.2988105123  0.030343540
[46,]  0.139060195  0.055819368 -0.1937205812 -0.3230992373 -0.023402058
[47,] -0.106882457 -0.100274480  0.1776645462 -0.1786404359 -0.031874712
[48,]  0.162874000  0.048320452  0.0499793759 -0.0746475432  0.032971397
[49,] -0.149286374  0.183544142 -0.0146956279  0.1779612297  0.209791844
[50,] -0.075741358  0.256123179 -0.1104181284  0.0895923465 -0.286742711
              PC16         PC17         PC18         PC19         PC20
 [1,]  0.157940786  0.029997504 -0.292465609  0.116430638  0.081323845
 [2,]  0.044469208 -0.119015831 -0.014291059 -0.197078579  0.238355940
 [3,]  0.078727526 -0.120676517 -0.062934337  0.032209482  0.269020548
 [4,]  0.197469349  0.101007167 -0.067287300  0.065479732 -0.148918599
 [5,]  0.101845576 -0.132819630 -0.036179960  0.150729456 -0.101538905
 [6,] -0.158057265 -0.106833777  0.116158911 -0.123001138  0.086484819
 [7,]  0.094961698 -0.293016113  0.202830099 -0.025857567  0.002680321
 [8,]  0.100793592 -0.210478210  0.062321154 -0.060203688 -0.154150540
 [9,] -0.033171701  0.251658296 -0.077850930 -0.069054593  0.031795454
[10,] -0.055140232  0.007899536  0.083566663 -0.315146759 -0.014189068
[11,]  0.111390406 -0.228296240 -0.042349380 -0.025970333 -0.141372850
[12,] -0.202428168 -0.162070486 -0.147334102  0.062569881 -0.080859865
[13,]  0.117031674  0.277425348 -0.071562592 -0.131925000  0.064835890
[14,]  0.007069339 -0.145547091  0.135915082  0.074453589  0.017458015
[15,]  0.067343136 -0.006582200 -0.136306461 -0.165260211 -0.156044495
[16,] -0.059205484  0.209746381 -0.165922334  0.093568636 -0.118393701
[17,] -0.019773630  0.086682418 -0.127331343 -0.048675822  0.187679957
[18,]  0.078554846 -0.039997840 -0.220578011  0.130852299 -0.109140063
[19,]  0.260366176  0.130715576  0.201397498 -0.183000843 -0.075862230
[20,] -0.176865095  0.270687263  0.106036033 -0.139057148 -0.217257230
[21,] -0.226515229 -0.105910708  0.036661107 -0.015672207  0.065481620
[22,]  0.069318633  0.039599648  0.277675750  0.198756099 -0.241158543
[23,]  0.012231926 -0.063444044 -0.248941922 -0.186833188  0.024968185
[24,] -0.208921914 -0.154284843 -0.146333519 -0.108900264 -0.263114318
[25,] -0.082311944  0.225114188 -0.083158233  0.181093859 -0.199646301
[26,] -0.055880242  0.168893707 -0.034321901 -0.138823126 -0.012896693
[27,] -0.131294543 -0.079744899 -0.231248829  0.054294631 -0.062946475
[28,]  0.228148421  0.190544412  0.058860041  0.126045389  0.155172403
[29,]  0.107142520 -0.171848675 -0.062820016 -0.193854758  0.091109649
[30,]  0.127327761  0.072790835  0.199499575 -0.149693049  0.059875261
[31,]  0.152347118  0.021626345  0.093468668  0.104308872 -0.007098285
[32,] -0.277771167  0.062275182  0.108793211  0.192989095 -0.267321777
[33,]  0.192620111 -0.108353344 -0.060098879  0.253154867  0.247383100
[34,] -0.166046633 -0.029359460  0.148716720 -0.015857986  0.096576370
[35,] -0.153823888  0.130421898  0.084841671  0.062132483  0.228641545
[36,] -0.089415136  0.087654310  0.240154945  0.023399155  0.085966066
[37,]  0.221031920 -0.051699124 -0.036402213  0.112272884 -0.202108616
[38,] -0.219521551 -0.127922824 -0.113295710 -0.084825550  0.215493295
[39,] -0.076179849  0.046022237  0.205187184 -0.142799897  0.029734045
[40,] -0.181758299  0.063396679 -0.026360018  0.257108153  0.139251692
[41,] -0.113743410  0.002060014 -0.007356113 -0.062399015 -0.028709703
[42,]  0.193953205 -0.097288505  0.074376446  0.009824625 -0.106708539
[43,]  0.092023612  0.050116970 -0.012218925  0.271901573  0.195800792
[44,] -0.083941040 -0.068066614  0.171978247  0.096643088 -0.066311941
[45,]  0.176325718 -0.028783676  0.002013910  0.011187741 -0.074683026
[46,] -0.026442812 -0.122666483 -0.067848564 -0.088397064 -0.101760956
[47,] -0.066724912  0.229008587  0.082032888  0.117671040  0.154318064
[48,]  0.006349858  0.156125287 -0.316058765 -0.186276444  0.025429292
[49,]  0.047460310 -0.014420762  0.192157806 -0.155014319  0.064137061
[50,] -0.210781328 -0.209457411  0.028513320  0.227555225  0.093777502
              PC21         PC22         PC23          PC24          PC25
 [1,]  0.023790050  0.045922678 -0.066189722 -0.1724427896  0.0738057514
 [2,] -0.231859444 -0.041088949 -0.159015991  0.0190142393 -0.0404572285
 [3,]  0.013426882 -0.092828422 -0.082675676 -0.1878235829 -0.0146970004
 [4,] -0.093315341 -0.056007201  0.214795681 -0.0724890454  0.2294171887
 [5,]  0.068253551 -0.014221205  0.028167604 -0.2565224685 -0.0782288162
 [6,] -0.033162321  0.343095876 -0.170030662  0.3339797410 -0.0713892085
 [7,]  0.056127239  0.092656234  0.039403397 -0.0316036192  0.1462774575
 [8,] -0.094283582 -0.084780888 -0.204029057  0.0004766342 -0.0811054208
 [9,] -0.171443865 -0.008836704  0.122122049  0.1343661270  0.2483131800
[10,] -0.107923868  0.062968092 -0.021221736 -0.0902549691  0.1758536741
[11,] -0.006150447 -0.077763967  0.088960459  0.3194424294 -0.0374330315
[12,]  0.057241515  0.001644633 -0.212314482 -0.0004988069 -0.1538886815
[13,]  0.137492659  0.005461060 -0.039217118 -0.1643495143 -0.1917291975
[14,]  0.254392257 -0.015294443  0.222652384 -0.0385711297 -0.0740680726
[15,]  0.251447078 -0.276454650 -0.281393910  0.0507517397 -0.0636237770
[16,] -0.131184126 -0.068934246  0.181066967  0.1610151215 -0.0763627731
[17,]  0.006838398  0.057362481 -0.031482716  0.0106740590  0.0532851484
[18,] -0.176523927 -0.074680481  0.176252473  0.0733182109 -0.0734166203
[19,]  0.185898477  0.149603750 -0.040057959 -0.0686546024 -0.0402677423
[20,] -0.054763689  0.132500961  0.038728807 -0.1850116253  0.0070467441
[21,] -0.118826692 -0.107506410 -0.178603712 -0.0639316781 -0.1082956759
[22,]  0.004358475  0.102163192 -0.107303487 -0.0254114813 -0.0743051454
[23,] -0.087268069  0.204818072  0.229324770 -0.0110115182 -0.0177331440
[24,] -0.038321042  0.091700958  0.073639216 -0.1170127251 -0.2410302545
[25,]  0.071497366  0.188230636 -0.316413574  0.2465106069  0.0966426866
[26,]  0.010195437 -0.121895937  0.054936399  0.1131771502 -0.0093023925
[27,] -0.032078555 -0.215539326 -0.033031376 -0.1007315762  0.1379805232
[28,] -0.015984490 -0.210270723 -0.031448224 -0.0159127067 -0.2183321163
[29,]  0.232372511  0.096226493  0.069384749  0.0067442165 -0.0003823659
[30,] -0.113747429 -0.311344029 -0.079429813  0.1848876219  0.0988188228
[31,] -0.077478600 -0.101529585  0.029755717 -0.1991813403 -0.0312260446
[32,]  0.303643070 -0.189781963 -0.130485814 -0.0660644832  0.1589775528
[33,]  0.221911290  0.157769106 -0.196016647  0.1945129613  0.3463047389
[34,]  0.161529561 -0.061965366  0.215395641  0.0478578061 -0.2577446726
[35,] -0.143463116 -0.013326934 -0.183369038  0.0582290295 -0.0037354399
[36,] -0.099456274  0.187299108  0.108145607 -0.0050035153 -0.0739485171
[37,] -0.010634051  0.071119054  0.049171577  0.1317909266 -0.1769870597
[38,]  0.167388545 -0.088904850  0.075832498  0.0419957778 -0.0810714569
[39,]  0.277264231 -0.175251411  0.189659991 -0.1204234444  0.3400268424
[40,] -0.085207424 -0.040470257  0.183611802 -0.0155673234  0.0378818166
[41,] -0.275619860 -0.131912796 -0.183605562 -0.1182747041  0.2045886505
[42,] -0.119918869  0.050818687  0.141197264  0.1431877507  0.1413019778
[43,] -0.088291123  0.158954898 -0.109634415 -0.3040542866 -0.1339340765
[44,] -0.128266316  0.323589567  0.004260433 -0.1767044100  0.1165840650
[45,] -0.117778564 -0.072696204  0.012225975  0.1604106745 -0.0629770555
[46,] -0.113507122  0.058552059  0.014734622 -0.0563664438  0.0735585651
[47,]  0.133329897  0.003185259  0.119718834  0.2497129385 -0.2112170930
[48,]  0.234940487  0.246539542  0.031528428 -0.0559989375  0.0704199578
[49,] -0.118068676 -0.102618722  0.013900611 -0.0667181191 -0.1252918941
[50,] -0.024748802 -0.072694420  0.229436483  0.0782495958  0.1363255266
              PC26          PC27          PC28         PC29         PC30
 [1,]  0.054050182  0.2409224331 -0.0004764633 -0.312047287 -0.179192921
 [2,]  0.165324087  0.1417371609 -0.0717683420  0.118589515 -0.067540476
 [3,] -0.194085038  0.0617887178  0.0597487348 -0.192244373  0.032385734
 [4,]  0.123397425  0.2379047173  0.1178953664  0.048190852  0.098201056
 [5,] -0.153414774 -0.0158804658 -0.1987305118  0.180488110  0.067631908
 [6,] -0.152191571 -0.0300744838 -0.1852879662 -0.075660371 -0.035336100
 [7,] -0.051956503  0.2154881164 -0.0221571590  0.277607848  0.075440554
 [8,] -0.024622020 -0.0503638810  0.2896571303 -0.303455434 -0.036210407
 [9,]  0.188610581 -0.1997975344 -0.0554931035 -0.022447866  0.122863577
[10,]  0.093149661  0.1525521931  0.0349944299 -0.120688559 -0.034831399
[11,] -0.146632422  0.0004717992  0.0765210340  0.025024306  0.010469475
[12,]  0.257604723  0.0824108648 -0.1510385600 -0.090098338  0.239075718
[13,]  0.101184282 -0.1631476432  0.1457509351  0.141728945 -0.238143570
[14,]  0.138195154  0.0263092899 -0.0854283323 -0.009986356  0.051108863
[15,] -0.102976579  0.0712261879  0.0065800426  0.078339616  0.006337413
[16,]  0.236326483  0.1913527674 -0.0760196185 -0.054299277 -0.050990383
[17,] -0.396797577  0.0836422465 -0.0450094760  0.256412201 -0.189284157
[18,] -0.149127956 -0.0087746953  0.0638139201 -0.005032653 -0.290560184
[19,] -0.033379497 -0.0970056972 -0.1056733205 -0.142668312  0.163478465
[20,] -0.017318915 -0.0068731308  0.2832758765  0.275834411  0.096697467
[21,]  0.055268456 -0.1828257625 -0.1053083552  0.127599822 -0.166366815
[22,]  0.068223993  0.1071881434  0.1737075401  0.129113161 -0.076272372
[23,]  0.014437144 -0.2912030693 -0.0585991667  0.158437445  0.078092865
[24,]  0.109672742  0.1270318055  0.1538959793  0.064505663 -0.172089325
[25,]  0.022368181  0.1171047634 -0.1638685712  0.064775237  0.027555030
[26,] -0.317607670 -0.1358552047 -0.0308303621 -0.003824004  0.267381226
[27,] -0.096059983 -0.1726017813  0.0025284254 -0.022485024  0.023944277
[28,]  0.026225033 -0.0417264373 -0.2642453329  0.045293280  0.250850086
[29,]  0.127137553  0.0254240889  0.0116270536 -0.142740873  0.007017237
[30,]  0.043812609 -0.0545106726 -0.0715086291 -0.021294548 -0.360392229
[31,]  0.017934114 -0.2227909663  0.0118018448  0.013905284 -0.171226224
[32,] -0.089896565 -0.0924654598 -0.0111639605 -0.114461944 -0.009429399
[33,]  0.218594297 -0.0923528688  0.3109835777  0.197035898  0.008203404
[34,] -0.058625326 -0.0281240556  0.2548710415 -0.079161729  0.039480253
[35,] -0.190424510  0.1230845868  0.1474413764  0.015709550 -0.032004164
[36,]  0.045006177  0.2292673561 -0.0544331556 -0.132837183 -0.138109418
[37,]  0.092539552 -0.0712268880 -0.3770233640  0.053673126 -0.156316826
[38,]  0.251181022 -0.1160308432  0.0335499317 -0.006160551  0.044587881
[39,]  0.010006710  0.0731408434 -0.2239191352 -0.051761023 -0.181736997
[40,] -0.168076280  0.2410095302 -0.0716786553 -0.205289866  0.094298935
[41,]  0.211959330 -0.1138999813 -0.0158028227 -0.021939039  0.190322140
[42,] -0.063954178 -0.1758219322  0.1140918443 -0.184978128  0.098249780
[43,]  0.005503398 -0.0935825454  0.0523777482  0.011146979  0.125546484
[44,] -0.075015332 -0.3028894638 -0.1442206706 -0.184531884 -0.134533557
[45,] -0.118181656  0.0471605309  0.1511954245  0.038470688  0.170573812
[46,] -0.134980637  0.0094067902  0.0259998346 -0.149135998  0.173941818
[47,]  0.093632520 -0.1216994601  0.1792566588 -0.150817975  0.008097333
[48,] -0.115032234  0.1034274331 -0.0233955631 -0.009831447 -0.005706415
[49,]  0.041754319  0.2283319648 -0.0653484626  0.153145837  0.233022252
[50,] -0.001771063 -0.0332582634 -0.0238324522  0.271681826 -0.009426303
             PC31         PC32         PC33         PC34         PC35
 [1,]  0.01095345  0.154714455  0.044800026 -0.138107138 -0.154726252
 [2,]  0.14671488 -0.097697227 -0.057921837 -0.251629625  0.089258591
 [3,]  0.11207795  0.016080920  0.026202362  0.231871876  0.212737552
 [4,] -0.14097075  0.023688932  0.082523958 -0.236282027  0.245272762
 [5,] -0.32410177  0.213292405 -0.008021793 -0.031995333 -0.059216445
 [6,] -0.12402717 -0.168034051  0.099929801  0.043666978  0.153756927
 [7,] -0.18828746 -0.130497881  0.024308653 -0.023850032  0.114063235
 [8,] -0.10185744 -0.017142232 -0.286021050 -0.157230038 -0.074253787
 [9,]  0.13815394  0.037742040  0.021861646  0.184442048 -0.083036688
[10,] -0.07943763 -0.045240444 -0.149590020  0.127408777 -0.272515137
[11,]  0.01961550 -0.015847529 -0.098000339  0.088576119 -0.157855014
[12,]  0.01705258  0.010013171  0.034761806 -0.184389082 -0.016802382
[13,] -0.14386590 -0.327788888 -0.121864773 -0.056757803  0.220742169
[14,]  0.13069454 -0.217716795 -0.077399846  0.229952369 -0.187149002
[15,]  0.25929027  0.042133570  0.332441989 -0.030111633  0.119132198
[16,]  0.04344216 -0.082405305  0.029641181  0.069606860 -0.021194886
[17,]  0.19633815 -0.075761051  0.094803467  0.087388080 -0.054600369
[18,]  0.01017904  0.155331086  0.015689527 -0.015098677 -0.032590475
[19,]  0.18001991  0.240060357 -0.066215683  0.020928919 -0.183325303
[20,]  0.12061385  0.131437332  0.229740109 -0.105340324  0.047884757
[21,] -0.06208806  0.057023176  0.251447288 -0.191447320 -0.221496136
[22,]  0.18412048  0.142450551 -0.043176172  0.287612674 -0.054050287
[23,]  0.14502476 -0.007505363 -0.274834083 -0.007805624  0.228460420
[24,] -0.17526643  0.061604888  0.003863575  0.231994015 -0.048178969
[25,] -0.03718864 -0.114253253 -0.125749585 -0.109713751 -0.112059724
[26,] -0.03085785  0.026000631 -0.126572757 -0.237352841 -0.218128062
[27,] -0.05590564 -0.076256156 -0.000515412  0.216156546  0.135678426
[28,] -0.15681744  0.273882115 -0.138725181  0.027411659  0.164601476
[29,] -0.07204092 -0.008893880  0.047050003  0.039252051  0.223161443
[30,] -0.09416527  0.135505266  0.100604660  0.038895309 -0.008605694
[31,]  0.17836072 -0.218327506 -0.125031676 -0.117246283 -0.166554937
[32,]  0.04598101 -0.101853185 -0.188285560  0.021119386  0.276950775
[33,]  0.08687215  0.133839736  0.027513141 -0.052600329 -0.021580381
[34,]  0.15072337  0.092255026 -0.003592337 -0.239639626  0.041779902
[35,] -0.09816963  0.183483291 -0.299061206  0.260249882  0.061107734
[36,]  0.19272206  0.104276425 -0.186462434 -0.187637952  0.210464921
[37,]  0.17369333 -0.042323460 -0.010907551  0.085016074  0.088233094
[38,]  0.07601618  0.233451846  0.032050429  0.061354604 -0.116907001
[39,] -0.09715404 -0.150452898 -0.003934985 -0.084256338 -0.128024825
[40,]  0.11190781 -0.111957824  0.162901617 -0.009075269  0.032953012
[41,] -0.07507798 -0.048102927 -0.050607974  0.136155316  0.094673151
[42,] -0.04759536 -0.033308076  0.298158114  0.102116925  0.047989936
[43,]  0.01097223 -0.324827300  0.110746292  0.058928518 -0.244888290
[44,] -0.11575237  0.204207988  0.205909400 -0.107886031  0.105537675
[45,] -0.15694018 -0.214980233 -0.029420446 -0.153705180 -0.071785497
[46,]  0.25685793 -0.104911280  0.033113576 -0.047879670 -0.003659788
[47,] -0.31782575 -0.107970954  0.213543996  0.043648679 -0.001912376
[48,] -0.20996276  0.103703972 -0.057076365  0.049623850 -0.139150082
[49,] -0.03360435 -0.011412800  0.162661601  0.166548232 -0.032230640
[50,] -0.01850972  0.106669430 -0.176561977 -0.129187770 -0.093470491
              PC36          PC37         PC38          PC39         PC40
 [1,] -0.197942719  0.2200722917  0.064685169 -0.0764512988 -0.121881079
 [2,]  0.227786008  0.1046237452 -0.136984377  0.0157833032 -0.111374142
 [3,]  0.079741166 -0.0466337679 -0.219617224 -0.1384384415  0.250763990
 [4,] -0.080149946  0.0805421196  0.007106110  0.1543600694 -0.040958815
 [5,] -0.118542353 -0.1664040292 -0.225812545 -0.0732924809  0.160049793
 [6,] -0.092761217  0.2589845920 -0.084584169  0.1957743146  0.089088102
 [7,]  0.075919180 -0.0192600332  0.019925416 -0.1315542885  0.077013522
 [8,]  0.125421817 -0.0244069973  0.169982120  0.1253923591  0.033561940
 [9,]  0.062002576 -0.0594187341 -0.158133375 -0.1373018679  0.209808607
[10,] -0.099694471 -0.1961393226  0.167255642  0.2029690171  0.131301090
[11,] -0.269170510  0.0006550095 -0.112036312 -0.0479775684  0.102799943
[12,]  0.046060673 -0.0573156939 -0.036278033  0.1215049701  0.133912563
[13,] -0.155862415  0.1263662421 -0.002471933  0.0115697801  0.287884378
[14,] -0.051909953  0.3585365815  0.001416975 -0.0907478805 -0.107741678
[15,] -0.128543600 -0.0470074602 -0.046663243  0.1768349936  0.205047590
[16,] -0.224313566 -0.1112339699 -0.082488910 -0.0084306299  0.222454046
[17,] -0.112594794 -0.1707938623 -0.067571955  0.2028440258 -0.269765053
[18,]  0.100591064  0.2058488443  0.242400871 -0.1750689756  0.102429995
[19,] -0.156604006  0.0580855909 -0.018219708  0.0683932741 -0.021103159
[20,]  0.066677629  0.0919877972  0.044487390 -0.1165961090  0.010480284
[21,] -0.106819466  0.0271003294  0.245881223 -0.2280878361  0.059506416
[22,]  0.280571400  0.0801388711  0.005394423  0.1454355611  0.146364652
[23,]  0.009895848  0.1133144514  0.192797508  0.1001935242 -0.078637506
[24,]  0.075255560 -0.0565815723 -0.193129110  0.2766497085 -0.223439109
[25,]  0.059813660 -0.1612678189 -0.068082058 -0.2075966023 -0.204087050
[26,]  0.205496425  0.0496604484  0.051968121  0.1184606995  0.205353229
[27,]  0.111585506 -0.2374545356  0.204222499  0.1208991528 -0.212502130
[28,] -0.016703021  0.0330429480  0.062808722  0.2425505591 -0.205100360
[29,]  0.065733460 -0.2136694170  0.085157278 -0.2297307817  0.098205891
[30,]  0.040147906  0.1941230904 -0.135049722 -0.0026121748 -0.188122279
[31,]  0.096745711 -0.1671138849 -0.239053458  0.0400020773 -0.012711865
[32,] -0.105028037  0.2637573817  0.022222363 -0.1042498174 -0.128942553
[33,]  0.040087104 -0.0693434705  0.145805994  0.1182010971  0.002841752
[34,]  0.001425711 -0.2591498636 -0.159322952 -0.2360188948 -0.220285937
[35,] -0.073297207 -0.0748434669  0.104641293 -0.2169739799  0.110163277
[36,] -0.153252881 -0.1552975175 -0.059190194  0.0279013679 -0.046861396
[37,]  0.218634701 -0.2092393492  0.191899106 -0.1594874547  0.004865832
[38,]  0.137870107  0.1414313038 -0.129131564  0.0175635155 -0.031141936
[39,]  0.142070251 -0.1382493943  0.094455827  0.0753340937  0.019317586
[40,]  0.328450174  0.1147273302  0.034044166  0.1739899410  0.149122985
[41,] -0.081251607  0.0231936896 -0.214399438 -0.1355108024 -0.107506862
[42,] -0.077491014 -0.0368897337 -0.168228812  0.0008449374 -0.148004296
[43,] -0.097269672  0.0332534267  0.012209599  0.0423375065 -0.062071560
[44,]  0.050367910  0.0116421109 -0.029838750  0.0389296439  0.079603571
[45,]  0.174434609  0.1026957494 -0.166954529 -0.1449683180 -0.064185169
[46,] -0.220066923 -0.0186452817  0.198817448 -0.0818393135 -0.128687747
[47,] -0.034062844 -0.1568618427  0.181520675  0.0977143406 -0.074734901
[48,]  0.211687364  0.1278250966 -0.140988221 -0.1791271152 -0.105986884
[49,] -0.040788779  0.0577191677  0.325281417 -0.1611719384 -0.108816350
[50,] -0.246689412  0.0492601299 -0.052542974  0.1244773183  0.120714894
               PC41          PC42         PC43         PC44         PC45
 [1,] -0.0958882279 -0.0738677769  0.240613491  0.160426265  0.061920876
 [2,] -0.0769814218 -0.2179205401 -0.076463309  0.084155807 -0.051995352
 [3,]  0.1907299231  0.0966256912  0.086165811 -0.222432578 -0.138035208
 [4,]  0.2504986366  0.0794424270 -0.222489334  0.177010545 -0.150075652
 [5,]  0.0129025843 -0.3154684528  0.139711256  0.043010662  0.025633475
 [6,]  0.1774670482 -0.2018862001  0.123337736  0.147643038  0.091313217
 [7,] -0.2102969511  0.1135321673 -0.087945483 -0.060382833 -0.282558616
 [8,] -0.0087650818 -0.1120429533  0.085853549  0.192971247 -0.208447197
 [9,]  0.0778324458 -0.1905674313 -0.225787586  0.108018388 -0.017384330
[10,]  0.1856344199 -0.0764849528 -0.071558923 -0.257830406  0.058709099
[11,]  0.2054370719  0.3050676130  0.024741086 -0.041733526 -0.065227293
[12,] -0.1339153847  0.2017164809 -0.230770043  0.281150516  0.020432080
[13,] -0.1557753682  0.0379008592  0.070641814 -0.096064443  0.061967846
[14,]  0.0310236284 -0.0980702024 -0.080471187  0.081493318 -0.139389319
[15,] -0.1863497043 -0.0114443096 -0.024432858 -0.118695564 -0.057380507
[16,] -0.1528208103 -0.2358439929  0.089150598 -0.024258756 -0.081395046
[17,] -0.0036726194 -0.0297150288 -0.077174507  0.280352076  0.073864764
[18,] -0.0344509622  0.0342177047  0.033432067 -0.020790547  0.076341095
[19,] -0.0431485314 -0.0978812125 -0.165560566 -0.002672882 -0.310244913
[20,]  0.2043355456  0.1489154739  0.153367672  0.144447491 -0.103038451
[21,]  0.2899217364 -0.0087614300 -0.163884394 -0.150558668 -0.075389632
[22,]  0.0304039930 -0.1770071441  0.130260871  0.088416392  0.234544083
[23,] -0.0421842436  0.0029053987  0.158713551 -0.043395692 -0.163417079
[24,]  0.0067912113  0.1367161847 -0.097154949 -0.151418759  0.086064969
[25,]  0.0978300194  0.1194220530  0.294330518 -0.096060975 -0.173388415
[26,] -0.0256177694  0.0827176789  0.187495713  0.017338421  0.119687238
[27,]  0.0322330827 -0.2619504332  0.057723987 -0.016975213 -0.286730636
[28,]  0.1702363183  0.1126436572 -0.024338455 -0.105693239  0.188900107
[29,]  0.3778663158  0.0308932072  0.056886135  0.284706837  0.295090662
[30,]  0.0993430455  0.0390374997 -0.034198140 -0.035190905 -0.083943770
[31,] -0.0116741764  0.1652327842 -0.126563270  0.164026493  0.153504480
[32,]  0.0574647217 -0.0547499301 -0.154891509 -0.040141194  0.106840632
[33,] -0.0291319212 -0.0696926378 -0.016232475 -0.221633404  0.131884786
[34,]  0.0086031963 -0.3008026406  0.027146827 -0.016738044 -0.004604820
[35,] -0.2463261121  0.1958635847 -0.218253820  0.279991539 -0.074453237
[36,] -0.0008160286  0.1288512622  0.088187964 -0.272662773 -0.042490910
[37,] -0.0306125001  0.1017371018 -0.080945784 -0.014599122  0.001999623
[38,] -0.1116606788  0.2371229875  0.208628640 -0.036896844 -0.073951580
[39,] -0.1269065965  0.1313875448  0.203696682  0.064721950  0.084671586
[40,]  0.0805093143  0.0204664616 -0.031757438 -0.125030015 -0.073508070
[41,] -0.0803563507  0.0398064644  0.189416223 -0.031751401  0.166109844
[42,] -0.2008224137  0.1605496741  0.180835601  0.099550196 -0.010040387
[43,]  0.1393766413  0.1121520350  0.059574544 -0.003457477 -0.113031629
[44,] -0.2392466813  0.0003311728 -0.106672882 -0.086601497  0.019642965
[45,] -0.0730628174 -0.1289193081 -0.135722643 -0.252620512  0.158112938
[46,] -0.1138019752  0.0514188653 -0.178028081 -0.152554430  0.366867682
[47,] -0.1120573066  0.0122260518 -0.114930323  0.024289302 -0.039761484
[48,] -0.0659081527 -0.0217788351 -0.262030705 -0.115436014  0.061081009
[49,] -0.2032469276 -0.0801853207  0.168519969  0.012801597  0.132207213
[50,] -0.0180292811 -0.0550343516  0.007065797  0.047183893  0.087159838
              PC46         PC47          PC48        PC49         PC50
 [1,] -0.168571259 -0.045439066 -6.409172e-02 -0.03931624  0.037422725
 [2,] -0.012600496 -0.188961150 -5.760995e-02 -0.06995691  0.266172249
 [3,]  0.036114184  0.006485126 -1.079845e-01  0.16464350  0.108179226
 [4,]  0.031477794 -0.061876823  2.309806e-01  0.07701797  0.194119204
 [5,] -0.026267090 -0.042450713  1.967080e-01 -0.08843569  0.042269743
 [6,]  0.076171556  0.011495421 -2.068740e-02  0.05801410  0.154624520
 [7,]  0.326726149 -0.002126200 -8.907648e-02 -0.13264885 -0.180301907
 [8,]  0.210844444  0.061202935 -4.370732e-02 -0.06227198 -0.157201810
 [9,] -0.084182575 -0.263286092  9.720912e-02 -0.18474916 -0.245041820
[10,]  0.125147604  0.177537465  2.015946e-01 -0.06446887  0.175583997
[11,] -0.285405029 -0.058138368  6.659986e-02  0.02081321  0.163621849
[12,] -0.178817511  0.094730678  1.273055e-01  0.16140030 -0.154919661
[13,] -0.046218279 -0.148882649  2.135598e-01  0.29131563 -0.053676827
[14,] -0.066455431  0.119759729  1.552191e-01  0.02590080 -0.211714322
[15,] -0.078108646  0.075687390 -1.289635e-01 -0.32017311 -0.100423993
[16,]  0.297211483  0.284808560 -1.676242e-01  0.17024767 -0.043924501
[17,]  0.137992241 -0.011484316  1.770664e-01 -0.03978012 -0.067037508
[18,]  0.151719964 -0.133147200  4.831709e-02 -0.23027921 -0.005538717
[19,] -0.024876955 -0.229060425 -1.745584e-01  0.05504448  0.160239927
[20,] -0.047950593  0.254218597 -1.618058e-01  0.04501852  0.133040341
[21,]  0.124174575 -0.277551591 -8.205588e-02  0.14907453 -0.142412888
[22,] -0.015859569 -0.102588926 -1.105360e-01  0.09666588 -0.022029115
[23,] -0.123032714  0.082079949 -1.388773e-01 -0.11866496 -0.178425460
[24,] -0.078276490 -0.191826182  1.221363e-02 -0.06517770 -0.137096248
[25,]  0.007775683 -0.101861308 -3.134927e-02  0.12054836 -0.117874540
[26,]  0.047952958  0.002187916  2.373825e-01 -0.06093553 -0.060940790
[27,] -0.221856474 -0.037180560 -5.566120e-02  0.26217295  0.091829130
[28,]  0.188197229  0.045322616 -1.322218e-01  0.07619079 -0.152784517
[29,] -0.055917923  0.027615252 -1.579064e-01 -0.09664651 -0.170974647
[30,] -0.117415890  0.386197913  5.956680e-02  0.06123558 -0.218812908
[31,]  0.105810624 -0.052329167 -2.066035e-01  0.09224888  0.072811632
[32,]  0.144454754 -0.084550735  9.332600e-02 -0.17698661  0.145143812
[33,] -0.017458748  0.043815198  1.671959e-01  0.05196241 -0.040479603
[34,]  0.038767329  0.137009360  2.140367e-01  0.03039667 -0.038625150
[35,] -0.116138910  0.067792715  2.219962e-02  0.04527967  0.029838017
[36,] -0.141467367 -0.172146466  5.230181e-02 -0.16848956 -0.153178872
[37,]  0.027471942  0.176469181  1.770070e-01 -0.07774936  0.346895581
[38,]  0.230420903 -0.017899631  1.497537e-01  0.06306640  0.293911186
[39,] -0.147597132 -0.057328570 -1.435141e-01  0.01215184  0.028898408
[40,] -0.034848558 -0.067761680  2.078880e-02  0.03089378 -0.098795957
[41,]  0.053040885  0.027557861  8.728948e-05 -0.29241629  0.084987658
[42,]  0.207251903 -0.216508374  5.326429e-02  0.17635218 -0.106634730
[43,] -0.029875499  0.203933306  3.824886e-02 -0.30490347 -0.013244735
[44,] -0.172840440  0.207577114  9.119002e-02  0.04520459 -0.009485349
[45,] -0.321831775  0.086600020 -1.364707e-01  0.02538020  0.066753843
[46,]  0.139334051  0.069800302 -8.728183e-02  0.21960891 -0.011357392
[47,] -0.030804975 -0.093701757 -2.183057e-01 -0.26817297  0.212514936
[48,]  0.129169001  0.092900505 -1.664521e-01  0.05263930  0.007782515
[49,] -0.151658482 -0.131595341  1.178141e-01  0.09556046  0.025103645
[50,] -0.063731943  0.052810299 -3.564141e-01  0.03589827  0.088449642

BatchQC documentation built on Nov. 8, 2020, 8:30 p.m.