simulateSites: Simulate peak log-intensities for PTM sites

In tsunghengtsai/MSstatsPTM: Statistical Characterization of Post-translational Modifications

Description

simulateSites simulates a list of log2-intensities of multiple spectral features and PTM sites of one protein, in multiple MS runs and conditions.

Usage

simulateSites(nGroup, nRep, nSite, nFeature, mu, delta, sRep, sPeak)

Arguments

nGroup	An integer to specify the number of conditions.
nRep	An integer to specify the number of replicates per condition.
nSite	An integer to specify the number of PTM sites per protein.
nFeature	An integer to specify the number of features per site.
mu	A numeric to specify the overall mean log2-intensity.
delta	A numeric to specify the deviation of the mean log2-abundance of each group from the overall mean.
sRep	A numeric to specify the standard deviation for run-to-run variation.
sPeak	A numeric to specify the standard deviation in peak log2-intensities.

Value

A tibble with columns of site, group, run, feature, log2inty.

Examples

simulateSites(nGroup=2, nRep=2, nSite=2, nFeature=5, 25, c(0, 1), 0.2, 0.05)

tsunghengtsai/MSstatsPTM documentation built on Oct. 4, 2020, 5:51 p.m.