MSstatsPTM: MSstatsPTM: A package for statistical characterization of...
In tsunghengtsai/MSstatsPTM: Statistical Characterization of Post-translational Modifications
Description
Details
Normalization
Summarization
Estimation
Comparison
Description
The MSstatsPTM package provides four main functions for quantitative analysis
of PTMs
Details
Quantitative analyses of PTMs are supported by four main functions of
MSstatsPTM:
Normalization
PTMnormalize() normalizes the quantified peak intensities to correct
systematic variation across MS runs.
Summarization
PTMsummarize() summarizes log2-intensities of spectral features
(i.e., precursor ions in DDA, fragments in DIA, or transitions in SRM) into
one value per PTM site per run or one value per protein per run.
Estimation
PTMestimate() takes as input the summarized log2-intensities for
each PTM site, performs statistical modeling for the log2-abundance of the
site, and returns the estimates of model parameters for all PTM sites in all
experimental conditions.
Comparison
PTMcompareMeans() performs statistical testing for detecting changes
in PTM mean abundances between conditions.
tsunghengtsai/MSstatsPTM documentation built on Oct. 4, 2020, 5:51 p.m.
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Description Details Normalization Summarization Estimation Comparison
Description
The MSstatsPTM package provides four main functions for quantitative analysis of PTMs
Details
Quantitative analyses of PTMs are supported by four main functions of MSstatsPTM:
Normalization
PTMnormalize() normalizes the quantified peak intensities to correct
systematic variation across MS runs.
Summarization
PTMsummarize() summarizes log2-intensities of spectral features
(i.e., precursor ions in DDA, fragments in DIA, or transitions in SRM) into
one value per PTM site per run or one value per protein per run.
Estimation
PTMestimate() takes as input the summarized log2-intensities for
each PTM site, performs statistical modeling for the log2-abundance of the
site, and returns the estimates of model parameters for all PTM sites in all
experimental conditions.
Comparison
PTMcompareMeans() performs statistical testing for detecting changes
in PTM mean abundances between conditions.
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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