loadExpressionDrugSensitivityAssociation: Load gene expression and drug sensitivity correlation matrix

In nuno-agostinho/cTRAP: Identification of candidate causal perturbations from differential gene expression data

Load gene expression and drug sensitivity correlation matrix

Description

Load gene expression and drug sensitivity correlation matrix

Usage

loadExpressionDrugSensitivityAssociation(
  source,
  file = NULL,
  path = NULL,
  rows = NULL,
  cols = NULL,
  loadValues = FALSE
)

Arguments

source	Character: source of matrix to load; see listExpressionDrugSensitivityAssociation
file	Character: filepath to gene expression and drug sensitivity association dataset (automatically downloaded if file does not exist)
path	Character: folder where to find files (optional; file may contain the full filepath if preferred)
rows	Character or integer: rows
cols	Character or integer: columns
loadValues	Boolean: load data values (if available)? If FALSE, downstream functions will load and process directly from the file chunk by chunk, resulting in a lower memory footprint

Value

Correlation matrix between gene expression (rows) and drug sensitivity (columns)

See Also

Other functions related with the prediction of targeting drugs: as.table.referenceComparison(), listExpressionDrugSensitivityAssociation(), plot.referenceComparison(), plotTargetingDrugsVSsimilarPerturbations(), predictTargetingDrugs()

Examples

gdsc <- listExpressionDrugSensitivityAssociation()[[1]]
loadExpressionDrugSensitivityAssociation(gdsc)

nuno-agostinho/cTRAP documentation built on March 28, 2024, 3:59 p.m.