prioritise_targets_multiheatmap: Prioritise targets: multi-heatmap

In neurogenomics/MultiEWCE: Multi-Scale Target Explorer

Prioritise targets: multi-heatmap

Description

Prioritise targets: multi-heatmap

Usage

prioritise_targets_multiheatmap(
  top_targets,
  prioritise_targets_network_out,
  ctd_list = load_example_ctd(c("ctd_DescartesHuman.rds", "ctd_HumanCellLandscape.rds"),
    multi_dataset = TRUE),
  gene_order = NULL,
  hpo = HPOExplorer::get_hpo(),
  gencc_extra = list(),
  size = 6,
  width = 50,
  heights = NULL,
  show_plot = TRUE
)

Arguments

top_targets	A results table after it has been annotated with add_disease and add_symptom_results.
prioritise_targets_network_out	Output of prioritise_targets_network.
ctd_list	A named list of CellTypeDataset objects each created with generate_celltype_data.
gene_order	The order in which to show genes in heatmap x-axis.
hpo	Human Phenotype Ontology object, loaded from get_ontology.
gencc_extra	Extra rows to add to the diseases GenCC data.
size	Plot text size.
width	Width of the saved plot.
heights	Passed to wrap_plots.
show_plot	Print the plot to the console.

Examples

top_targets <- MSTExplorer::example_targets$top_targets[1:10]
prioritise_targets_network_out <- prioritise_targets_network(
  top_targets = top_targets)

out <- prioritise_targets_multiheatmap(
  top_targets = top_targets,
  prioritise_targets_network_out = prioritise_targets_network_out,
  ctd_list=load_example_ctd("ctd_DescartesHuman.rds", multi_dataset = TRUE))

neurogenomics/MultiEWCE documentation built on April 17, 2025, 9:27 p.m.