Description Usage Arguments Value Author(s) References See Also Examples
The function calculates the p-value threshold tau for a given false discovery rate. Tau is used for the scoring function.
1 | fdrThreshold(fdr, fb)
|
fdr |
False discovery rate. |
fb |
Model from the beta-uniform mixture fitting. |
P-value threshold tau.
Marcus Dittrich
S. Pounds, S.W. Morris (2003) Estimating the occurrence of false positives and false negatives in microarray studies by approximating and partitioning the empirical distribution of p-values. Bioinformatics, 19(10): 1236-1242.
1 2 3 4 5 | data(pvaluesExample)
pvals <- pvaluesExample[,1]
bum.mle <- fitBumModel(pvals, plot=FALSE)
tau <- fdrThreshold(fdr=0.001, fb=bum.mle)
tau
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