add_p_q_values_statistics: add_p_q_values_statistics

In RaikOtto/Younikorn: Identification of cancer cell lines based on their weighted mutational/ variational fingerprint

add_p_q_values_statistics

Description

A hypergeometric distribution-assumption allows to calculate the p-values for a significant or non-significant overlap in this function

Usage

add_p_q_values_statistics(
  g_query,
  match_t,
  p_value,
  ref_gen,
  minimum_matching_mutations,
  top_hits_per_library
)

Arguments

g_query	IRanges object that contains the query variants
match_t	A table that contains the nubmber of matching variants
p_value	Threshold for the significance p-value
ref_gen	Reference genome version
minimum_matching_mutations	Manual lower amount of matching mutations require for a significant match between a query and a reference
top_hits_per_library	limits significant similarities to the first n hits

Details

add_p_q_values_statistics Calculates the p-values

Value

R table with a statistic

RaikOtto/Younikorn documentation built on Oct. 18, 2022, 1:21 a.m.