Description Usage Arguments Value See Also Examples
Get Encode regulatory tables using a human DHS filter
1 2 | ## S4 method for signature 'HumanDHSFilter'
getEncodeRegulatoryTableNames(obj)
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obj |
An object of class HumanDHSFilter |
A character vector containing the names of the Encode regulatory tables for the regions contained in the HumanDHSFilter object
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 | load(system.file(package="trena", "extdata/ampAD.154genes.mef2cTFs.278samples.RData"))
targetGene <- "VRK2"
promoter.length <- 1000
genomeName <- "hg38"
db.address <- system.file(package="trena", "extdata")
genome.db.uri <- paste("sqlite:/", db.address, "vrk2.neighborhood.hg38.gtfAnnotation.db", sep = "/")
jaspar.human <- as.list(query(query(MotifDb, "sapiens"),"jaspar2016"))
# Grab regions for VRK2 using shoulder size of 1000
trena <- Trena(genomeName)
tbl.regions <- getProximalPromoter(trena, "VRK2", 1000, 1000)
hd.filter <- HumanDHSFilter(genomeName, pwmMatchPercentageThreshold = 85,
geneInfoDatabase.uri = genome.db.uri, regions = tbl.regions, pfms = jaspar.human)
getEncodeRegulatoryTableNames(hd.filter)
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