pathwayanalysis: Run Overrepresentation Analysis via the ClusterProfiler...

View source: R/pathwayanalysis.R

pathwayanalysisR Documentation

Run Overrepresentation Analysis via the ClusterProfiler workflow

Description

Run Overrepresentation Analysis via the ClusterProfiler workflow

Usage

pathwayanalysis(sigres, term2gene)

Arguments

sigres

data.frame of significant genes. first column is gene names; second column is logfoldchange or other effect size.

term2gene

data.frame of pathways to check. first column is pathways, second column is genes.

Value

a list object: first element is a ClusterProfiler object; second element is an "emap plot", a graph of pathways connected by jaccard similarity; third element is a data.frame with the connected nodes from the emap plot; 4th element is a list of pathways in each connected cluster; 5th element is genes from the pathways in each cluster


FerrenaAlexander/FerrenaBulkRNAseq documentation built on Oct. 16, 2022, 8:18 a.m.