write_ranges: Write GRanges to file

In multicrispr: Multi-locus multi-purpose Crispr/Cas design

Description

Write GRanges to file

Usage

write_ranges(gr, file, verbose = TRUE)

read_ranges(file, bsgenome)

Arguments

gr	GRanges-class
file	file
verbose	TRUE (default) or FALSE
bsgenome	BSgenome-class

Value

GRanges-class for read_ranges

Examples

# Find PE spacers for 4 clinically relevant loci (Anzalone et al, 2019)
    bsgenome <- BSgenome.Hsapiens.UCSC.hg38::BSgenome.Hsapiens.UCSC.hg38  
    gr <- char_to_granges(c(
        PRNP = 'chr20:4699600:+',             # snp: prion disease
        HBB  = 'chr11:5227002:-',             # snp: sickle cell anemia
        HEXA = 'chr15:72346580-72346583:-',   # del: tay sachs disease
        CFTR = 'chr7:117559593-117559595:+'), # ins: cystic fibrosis
        bsgenome)
    file <- file.path(tempdir(), 'gr.txt')
    write_ranges(gr, file)
    read_ranges(file, bsgenome)

multicrispr documentation built on Nov. 8, 2020, 5:10 p.m.