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This package is for designing Crispr/Cas9 and Prime Editing experiments. It contains functions to (1) define and transform genomic targets, (2) find spacers (4) count offtarget (mis)matches, and (5) compute Doench2016/2014 targeting efficiency. Care has been taken for multicrispr to scale well towards large target sets, enabling the design of large Crispr/Cas9 libraries.
Package details |
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Author | Aditya Bhagwat [aut, cre], Johannes Graumann [sad, ctb], Mette Bentsen [ctb], Jens Preussner [ctb], Michael Lawrence [ctb], Hervé Pagès [ctb], Mario Looso [sad, rth] |
Bioconductor views | CRISPR Software |
Maintainer | Aditya Bhagwat <aditya.bhagwat@mpi-bn.mpg.de> |
License | GPL-2 |
Version | 1.0.0 |
URL | https://loosolab.pages.gwdg.de/software/multicrispr/ |
Package repository | View on Bioconductor |
Installation |
Install the latest version of this package by entering the following in R:
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