Description Usage Arguments Details Value Note Examples
Compute SNP-by-SNP goodness-of-fit when compared to population structure. This can be aggregated to determine genome-wide goodness-of-fit for a particular value of d.
1 | model.gof(X, LF, B)
|
X |
a matrix of SNP genotypes, i.e. an integer matrix of 0's, 1's, and 2's. Sparse matrices of class Matrix are not supported (yet). |
LF |
matrix of logistic factors |
B |
number of null datasets to generate - B=1 is usualy sufficient. If computational time/power allows, a few extra B could be helpful |
This function returns p-values for LFA model goodness of fit based on a simulated null.
vector of p-values for each SNP.
Genotype matrix is expected to be a matrix of integers with values 0, 1, and 2. Currently no support for missing values. Note that the coding of the SNPs does not affect the algorithm.
1 2 3 4 5 6 | LF <- lfa(hgdp_subset, 4)
gof_4 <- model.gof(hgdp_subset, LF, 3)
LF <- lfa(hgdp_subset, 10)
gof_10 <- model.gof(hgdp_subset, LF, 3)
hist(gof_4)
hist(gof_10)
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