Description Usage Value Note Examples
provide access to a limma analysis of RNA-seq profiles for reference histology samples
1 |
an instance of MArrayLM-class
representing regularized gene-wise ANOVAs
Uses download.file
to acquire RDS of the output
of eBayes
from a public S3 bucket. The limma model
was fit using duplicateCorrelation
to address multiplicity
of contributions per donor. Comparisons are to samples labeled CT-reference
(cellular tumor, reference contributions),
with coefficients 2-5 corresponding to CT-mvp (microvascular proliferation),
CT-pan (pseudopalisading cells around necrosis), IT (infiltrating tumor),
and LE (leading edge), respectively.
1 2 3 4 | requireNamespace("limma")
ebout = getRefLimma() # is result of eBayes
colnames(ebout$coef)
limma::topTable(ebout,2)
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