getPotentialSwaps: Calculate swap partner for TF-/miRNA-target graph. This...

In birte: Bayesian Inference of Regulatory Influence on Expression (biRte)

Description

Calculates for TF-/miRNA-target graph all potential swap partner.

Usage

getPotentialSwaps(genesets, perc.overlap.cutoff=0.8, integer.id=TRUE) 

Arguments

genesets	Each entry corresponds to a regulator (miRNA, TF, other) and contains its target genes.
perc.overlap.cutoff	Percentage cutoff of minimal overlap between two miRNAs or TFs to be possible swap partner.
integer.id	If TRUE, the swap partner are not output as characters, but as integer indices.

Value

A list object, where each element corresponds to one regulator.

Author(s)

Holger Froehlich

Examples

# artificial data
data(humanNetworkSimul)
genesets = c(sapply(affinities2$TF, names), 
sapply(affinities2$miRNA, names), sapply(affinities2$other, names))
swaps = getPotentialSwaps(genesets)

birte documentation built on May 2, 2019, 12:32 a.m.