Selector: Select signatures from candidate list (according to the...

In MAGeCKFlute: Integrative Analysis Pipeline for Pooled CRISPR Functional Genetic Screens

Description

Select signatures from candidate list (according to the consistence in most samples).

Usage

Selector(mat, cutoff = 0, type = "<", select = 0.8)

Arguments

mat	Data matrix, each row is candidates (genes), each column is samples.
cutoff	Cutoff to define the signatures.
type	Direction to select signatures.
select	Proportion of samples in which signature is selected.

Value

An list containing two elements, first is selected signature and second is a ggplot object.

Examples

mat = matrix(rnorm(1000*30), 1000, 30)
rownames(mat) = paste0("Gene", 1:1000)
colnames(mat) = paste0("Sample", 1:30)
hits = Selector(mat, select = 0.68)
print(hits$p)

MAGeCKFlute documentation built on Nov. 8, 2020, 5:40 p.m.