Description Usage Arguments Value Examples
View source: R/get_fisher_info.R
Obtain a measure for strength and significance for the
relationship (i.e. an edge) based on the concordance/discordance of
UP-and-DOWN regulated genes shared by two different experimental
gene-knockouts
Intended for use within overlap_info
1 | get_fisher_info(edges, method)
|
edges |
The set of eges to be analyzed; Although the intended use is for LINCS data overlaps, the function should work with any typical data object as long as it has columns labeled ("UP", "DOWN", "UK1_DK2", "DK1_UK2") that contain integer values. |
method |
The method to correct/adjust p-values for multiple testing. For available methods, type 'p.adjust.methods' into command promt and press enter. |
The input edge data.frame object with additional columns containing the results of the applied statistical test
1 2 3 4 | ex.data <- data.frame("UP" = c(70,6), "DOWN" = c(8,20),
"UK1_DK2" = c(4,47), "DK1_UK2" = c(3, 28))
overlaps <- get_fisher_info(ex.data, method = "BH")
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