stableFeature: Generating Features

Description Usage Arguments Value Author(s) See Also Examples

View source: R/nucSim.R

Description

These functions are used to generate the parameters for different nucleosome positioning related features.

Usage

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stableFeature(start, minDist = 175, weight = seq(0.1, 1, by = 0.1), 
	shift = c(0, 5, 10), ratio = seq(0, 4, by = 0.25), 
	stability = seq(0.1, 5, by = 0.1), weightProb, shiftProb, 
	ratioProb, stabilityProb, ...)
phasedFeature(minDist = 175, length = seq(1000, 10000, by = minDist), 
	meanDist = minDist:300, lengthProb, meanDistProb, start, ...)
fuzzyFeature(start, length = seq(1000, 10000, by = 1000), 
	meanDist = 175:400, lengthProb, meanDistProb, ...)
nfrFeature(start, length = seq(50, 500, by = 10), 
	weight = seq(0.1, 1, by = 0.1), lengthProb, weightProb, ...)

Arguments

start

Start location of feature on chromosome.

minDist

Minimum distance between nucleosomes.

length

A numeric vector giving possible values for the length of the feature.

meanDist

A numeric vector giving possible values for the mean distance between nucleosomes.

weight

A numeric vector giving possible values for the weight of the feature.

shift

A numeric vector giving possible values for the distance between favoured positions of stable nucleosomes.

ratio

A numeric vector giving possible values for the ratio between probabilities for alternative and central position of stable nucleosomes.

stability

A numeric vector giving possible values for the stability of stable nucleosomes.

lengthProb

Length distribution of feature. This corresponds to the state duration distribution of the underlying generating model.

meanDistProb

Distribution of mean distances between nucleosomes.

weightProb

Distribution of feature weights.

shiftProb

Distribution of distances between favoured positions of stable nucleosome.

ratioProb

Ratio distribution.

stabilityProb

Stability distribution.

...

Further arguments (currently ignored).

Value

A list of parameters for the corresponding feature type. These parameters are later used to compute nucleosome densities.

Author(s)

Peter Humburg

See Also

simChIP

Examples

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feature <- stableFeature(200)

ChIPsim documentation built on Nov. 8, 2020, 8:09 p.m.