xEnrichViewer: Function to view enrichment results

In Pi: Leveraging Genetic Evidence to Prioritise Drug Targets at the Gene and Pathway Level

Description

xEnrichViewer is supposed to view results of enrichment analysis.

Usage

xEnrichViewer(
eTerm,
top_num = 10,
sortBy = c("adjp", "fdr", "pvalue", "zscore", "fc", "nAnno",
"nOverlap", "or",
"none"),
decreasing = NULL,
details = FALSE
)

Arguments

eTerm	an object of class "eTerm"
top_num	the number of the top terms (sorted according to 'sortBy' below) will be viewed
sortBy	which statistics will be used for sorting and viewing gene sets (terms). It can be "adjp" or "fdr" for adjusted p value (FDR), "pvalue" for p value, "zscore" for enrichment z-score, "fc" for enrichment fold change, "nAnno" for the number of sets (terms), "nOverlap" for the number in overlaps, "or" for the odds ratio, and "none" for ordering according to ID of terms
decreasing	logical to indicate whether to sort in a decreasing order. If it is null, it would be true for "zscore", "nAnno" or "nOverlap"; otherwise it would be false
details	logical to indicate whether the detailed information of gene sets (terms) is also viewed. By default, it sets to false for no inclusion

Value

a data frame with following components:

• id: term ID; as rownames

• name: term name

• nAnno: number in members annotated by a term

• nOverlap: number in overlaps

• fc: enrichment fold changes

• zscore: enrichment z-score

• pvalue: nominal p value

• adjp: adjusted p value (FDR)

• or: a vector containing odds ratio

• CIl: a vector containing lower bound confidence interval for the odds ratio

• CIu: a vector containing upper bound confidence interval for the odds ratio

• distance: term distance or other information; optional, it is only appended when "details" is true

• members_Overlap: members (represented as Gene Symbols) in overlaps; optional, it is only appended when "details" is true

• members_Anno: members (represented as Gene Symbols) in annotations; optional, it is only appended when "details" is true

Note

none

See Also

xEnrichViewer

Examples

RData.location <- "http://galahad.well.ox.ac.uk/bigdata"
## Not run: 
xEnrichViewer(eTerm)

## End(Not run)

Pi documentation built on Nov. 29, 2021, 3 p.m.