DLBC: Lymphoid Neoplasm Diffuse Large B-cell Lymphoma

In waldronlab/curatedTCGAData: Curated Data from The Cancer Genome Atlas (TCGA) as MultiAssayExperiment Objects

Lymphoid Neoplasm Diffuse Large B-cell Lymphoma

Description

A document describing the TCGA cancer code

Details

> experiments( DLBC )
ExperimentList class object of length 10: 
 [1] DLBC_CNASNP-20160128: RaggedExperiment with 44725 rows and 94 columns 
 [2] DLBC_CNVSNP-20160128: RaggedExperiment with 9343 rows and 94 columns 
 [3] DLBC_GISTIC_AllByGene-20160128: SummarizedExperiment with 24776 rows and 48 columns 
 [4] DLBC_GISTIC_Peaks-20160128: RangedSummarizedExperiment with 39 rows and 48 columns 
 [5] DLBC_GISTIC_ThresholdedByGene-20160128: SummarizedExperiment with 24776 rows and 48 columns 
 [6] DLBC_miRNASeqGene-20160128: SummarizedExperiment with 1046 rows and 47 columns 
 [7] DLBC_Mutation-20160128: RaggedExperiment with 16918 rows and 48 columns 
 [8] DLBC_RNASeq2GeneNorm-20160128: SummarizedExperiment with 20501 rows and 48 columns 
 [9] DLBC_RPPAArray-20160128: SummarizedExperiment with 192 rows and 33 columns 
 [10] DLBC_Methylation-20160128: SummarizedExperiment with 485577 rows and 48 columns 

> rownames( DLBC )
CharacterList of length 10
[["DLBC_CNASNP-20160128"]] character(0)
[["DLBC_CNVSNP-20160128"]] character(0)
[["DLBC_GISTIC_AllByGene-20160128"]] ACAP3 ... WASIR1|ENSG00000185203.7
[["DLBC_GISTIC_Peaks-20160128"]] chr1:1-48649489 ... chr22:41635693-51304566
[["DLBC_GISTIC_ThresholdedByGene-20160128"]] ACAP3 ...
[["DLBC_miRNASeqGene-20160128"]] hsa-let-7a-1 hsa-let-7a-2 ... hsa-mir-99b
[["DLBC_Mutation-20160128"]] character(0)
[["DLBC_RNASeq2GeneNorm-20160128"]] A1BG A1CF A2BP1 ... ZZZ3 psiTPTE22 tAKR
[["DLBC_RPPAArray-20160128"]] 14-3-3_beta ... p90RSK_pT359_S363
[["DLBC_Methylation-20160128"]] cg00000029 cg00000108 ... rs966367 rs9839873

> colnames( DLBC )
CharacterList of length 10
[["DLBC_CNASNP-20160128"]] TCGA-FA-8693-01A-11D-2389-01 ...
[["DLBC_CNVSNP-20160128"]] TCGA-FA-8693-01A-11D-2389-01 ...
[["DLBC_GISTIC_AllByGene-20160128"]] TCGA-FA-8693-01A-11D-2389-01 ...
[["DLBC_GISTIC_Peaks-20160128"]] TCGA-FA-8693-01A-11D-2389-01 ...
[["DLBC_GISTIC_ThresholdedByGene-20160128"]] TCGA-FA-8693-01A-11D-2389-01 ...
[["DLBC_miRNASeqGene-20160128"]] TCGA-FA-8693-01A-11R-2401-13 ...
[["DLBC_Mutation-20160128"]] TCGA-FA-8693-01A-11D-2397-10 ...
[["DLBC_RNASeq2GeneNorm-20160128"]] TCGA-FA-8693-01A-11R-2404-07 ...
[["DLBC_RPPAArray-20160128"]] TCGA-FA-8693-01A-21-A45K-20 ...
[["DLBC_Methylation-20160128"]] TCGA-FA-8693-01A-11D-2399-05 ...

Sizes of each ExperimentList element:

                                    assay size.Mb
1                    DLBC_CNASNP-20160128  1.2 Mb
2                    DLBC_CNVSNP-20160128  0.3 Mb
3          DLBC_GISTIC_AllByGene-20160128  4.9 Mb
4              DLBC_GISTIC_Peaks-20160128    0 Mb
5  DLBC_GISTIC_ThresholdedByGene-20160128  4.9 Mb
6              DLBC_miRNASeqGene-20160128  0.1 Mb
7                  DLBC_Mutation-20160128 12.6 Mb
8           DLBC_RNASeq2GeneNorm-20160128  1.3 Mb
9                 DLBC_RPPAArray-20160128    0 Mb
10              DLBC_Methylation-20160128   75 Mb

---------------------------
Overall survival time-to-event summary (in years):
---------------------------

Call: survfit(formula = survival::Surv(colDat$days_to_death/365, colDat$vital_status) ~ 
    -1)

   39 observations deleted due to missingness 
      n  events  median 0.95LCL 0.95UCL 
  9.000   9.000   1.630   0.858      NA 


---------------------------
Available sample meta-data:
---------------------------

years_to_birth:
   Min. 1st Qu.  Median    Mean 3rd Qu.    Max. 
  23.00   46.00   57.50   56.27   67.00   82.00 

vital_status:
 0  1 
39  9 

days_to_death:
   Min. 1st Qu.  Median    Mean 3rd Qu.    Max.    NA's 
     58     313     595    1505    1252    6425      39 

days_to_last_followup:
   Min. 1st Qu.  Median    Mean 3rd Qu.    Max.    NA's 
      0     616     946    1328    1581    5980       9 


gender:
female   male 
    26     22 

date_of_initial_pathologic_diagnosis:
   Min. 1st Qu.  Median    Mean 3rd Qu.    Max. 
   1987    2009    2011    2009    2012    2013 

radiation_therapy:
  no  yes NA's 
  40    7    1 

histological_type:
diffuse large b-cell lymphoma (dlbcl) nos (any anatomic site nodal or extranodal) 
                                                                               41 
                                                         primary dlbcl of the cns 
                                                                                3 
                                               primary mediastinal (thymic) dlbcl 
                                                                                4 

race:
                    asian black or african american                     white 
                       18                         1                        29 

ethnicity:
    hispanic or latino not hispanic or latino 
                    12                     36 

Including an additional 607 columns

See Also

DLBC-v2.0.1

waldronlab/curatedTCGAData documentation built on Nov. 4, 2024, 7:57 a.m.