tcgaDriverBP: Compare genes to known TCGA drivers and their biological...

Description Usage Arguments References Examples

View source: R/driverBP.R

Description

A small function which uses known cancer driver genes and their associatd pathways from TCGA cohorts. See reference for details

Usage

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tcgaDriverBP(m, genes = NULL, top = 20, fontSize = 0.7)

Arguments

m

an MAF object

genes

genes to compare. Default 'NULL'.

top

Top number of genes to use. Mutually exclusive with 'genes' argument. Default 20

fontSize

Default 0.7

References

Bailey MH, Tokheim C, Porta-Pardo E, et al. Comprehensive Characterization of Cancer Driver Genes and Mutations . Cell. 2018;173(2):371–385.e18. doi:10.1016/j.cell.2018.02.060

Examples

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laml.maf <- system.file("extdata", "tcga_laml.maf.gz", package = "maftools")
laml <- read.maf(maf = laml.maf)
tcgaDriverBP(m = laml)

thesushantpatil/maftools documentation built on May 18, 2020, 9:54 p.m.