CIMICE is a tool in the field of tumor phylogenetics and its goal is to build a Markov Chain (called Cancer Progression Markov Chain, CPMC) in order to model tumor subtypes evolution. The input of CIMICE is a Mutational Matrix, so a boolean matrix representing altered genes in a collection of samples. These samples are assumed to be obtained with single-cell DNA analysis techniques and the tool is specifically written to use the peculiarities of this data for the CMPC construction.
Package details |
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Bioconductor views | BiologicalQuestion GraphAndNetwork NetworkInference Phylogenetics ResearchField SingleCell Software StatisticalMethod Technology |
Maintainer | |
License | Artistic-2.0 |
Version | 1.3.1 |
URL | https://github.com/redsnic/CIMICE |
Package repository | View on GitHub |
Installation |
Install the latest version of this package by entering the following in R:
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