get.ensembl.annotation: Ensembl annotation downloader

In pmoulos/metaseqr: An R package for the analysis and result reporting of RNA-Seq data by combining multiple statistical algorithms.

Description

This function connects to the EBI's Biomart service using the package biomaRt and downloads annotation elements (gene co-ordinates, exon co-ordinates, gene identifications, biotypes etc.) for each of the supported organisms. See the help page of metaseqr for a list of supported organisms. The function downloads annotation for an organism genes or exons.

Usage

    get.ensembl.annotation(org, type)

Arguments

org	the organism for which to download annotation.
type	either "gene" or "exon".

Value

A data frame with the canonical (not isoforms!) genes or exons of the requested organism. When type="genes", the data frame has the following columns: chromosome, start, end, gene_id, gc_content, strand, gene_name, biotype. When type="exon" the data frame has the following columns: chromosome, start, end, exon_id, gene_id, strand, gene_name, biotype. The gene_id and exon_id correspond to Ensembl gene and exon accessions respectively. The gene_name corresponds to HUGO nomenclature gene names.

Note

The data frame that is returned contains only "canonical" chromosomes for each organism. It does not contain haplotypes or random locations and does not contain chromosome M.

Author(s)

Panagiotis Moulos

Examples

hg19.genes <- get.ensembl.annotation("hg19","gene")
mm9.exons <- get.ensembl.annotation("mm9","exon")

pmoulos/metaseqr documentation built on Dec. 29, 2020, 5:56 a.m.