##############################################
############# S4 Methods #############
##############################################
### Genomic Profiles internal MEthods
setMethod("PositionWeightMatrix","genomicProfilesInternal",
function(object) object@PWM
)
setReplaceMethod("PositionWeightMatrix",
signature(object="genomicProfilesInternal",
value="matrix"),
function(object, value){
object@PWM<-value
return(object)
}
)
setMethod("PositionFrequencyMatrix","genomicProfilesInternal",
function(object) object@PFM
)
setReplaceMethod("PositionFrequencyMatrix",
signature(object="genomicProfilesInternal",
value="matrix"),
function(object, value){
object@PFM<-value
return(object)
}
)
setReplaceMethod("PositionFrequencyMatrix",
signature(object="genomicProfilesInternal",
value="character"),
function(object,value){
value <- .parsePFM(value,object@PFMFormat)
object@PFM<-value
return(object)
}
)
setMethod("PFMFormat","genomicProfilesInternal",
function(object) object@PFMFormat
)
setReplaceMethod("PFMFormat",
signature(object="genomicProfilesInternal",
value="character"),
function(object, value){
object@PFMFormat<-value
return(object)
}
)
setMethod("BPFrequency","genomicProfilesInternal",
function(object) object@BPFrequency
)
setReplaceMethod("BPFrequency",
signature(object="genomicProfilesInternal",
value="vector"),
function(object, value){
object@BPFrequency<-value
return(object)
}
)
setReplaceMethod("BPFrequency",
signature(object="genomicProfilesInternal",
value="DNAStringSet"),
function(object, value){
value <- .computeBPFrequency(value)
object@BPFrequency<-value
return(object)
}
)
setMethod("naturalLog","parameterOptions",
function(object) object@naturalLog
)
setReplaceMethod("naturalLog",
signature(object="parameterOptions",
value="logical"),
function(object, value){
object@naturalLog<-value
return(object)
}
)
setMethod("minPWMScore","genomicProfilesInternal",
function(object) object@minPWMScore
)
setReplaceMethod(".minPWMScore", signature(object="genomicProfilesInternal",
value="vector"),
function(object,value){
object@minPWMScore<-value
return(object)
}
)
setMethod("maxPWMScore","genomicProfilesInternal",
function(object) object@maxPWMScore)
setReplaceMethod(".maxPWMScore", signature(object="genomicProfilesInternal",
value="vector"),
function(object,value){
object@maxPWMScore<-value
return(object)
}
)
setMethod("profiles","genomicProfilesInternal",
function(object) object@profiles
)
setReplaceMethod(".profiles", signature(object="genomicProfilesInternal",
value="GRList"),
function(object,value){
object@profiles<-value
return(object)
}
)
setMethod("DNASequenceLength","genomicProfilesInternal",
function(object) object@DNASequenceLength
)
setReplaceMethod(".DNASequenceLength",
signature(object="genomicProfilesInternal",
value="vector"),
function(object, value){
object@DNASequenceLength<-value
return(object)
}
)
setMethod("averageExpPWMScore","genomicProfilesInternal",
function(object) object@averageExpPWMScore
)
setReplaceMethod(".averageExpPWMScore",signature(object= "genomicProfilesInternal",
value="numeric"),
function(object,value){
object@averageExpPWMScore<-value
return(object)
}
)
setMethod("drop","genomicProfilesInternal",
function(object) object@drop
)
setReplaceMethod(".drop",signature(object= "genomicProfilesInternal",
value="vector"),
function(object, value){
object@drop <- value
return(object)
}
)
setMethod(".tags","genomicProfilesInternal",
function(object) object@tags
)
setReplaceMethod(".tags",
signature(object="genomicProfilesInternal",
value="character"),
function(object, value){
object@tags<-value
return(object)
}
)
## parameterOption methods
setMethod("PWMThreshold","parameterOptions",
function(object) object@PWMThreshold
)
setReplaceMethod("PWMThreshold",
signature(object="parameterOptions",
value="numeric"),
function(object, value){
object@PWMThreshold<-value
return(object)
}
)
setMethod("strandRule","parameterOptions",
function(object) object@strandRule
)
setReplaceMethod("strandRule",
signature(object="parameterOptions",
value="character"),
function(object, value){
object@strandRule<-value
return(object)
}
)
setMethod("whichstrand","parameterOptions",
function(object) object@whichstrand
)
setReplaceMethod("whichstrand",
signature(object="parameterOptions",
value="character"),
function(object, value){
object@whichstrand<-value
return(object)
}
)
setMethod("lambdaPWM", "parameterOptions",
function(object) object@lambdaPWM
)
setReplaceMethod("lambdaPWM",
signature(object="parameterOptions",
value="vector"),
function(object,value){
object@lambdaPWM<-value
return(object)
}
)
setMethod("noOfSites", "parameterOptions",
function(object) object@noOfSites
)
setReplaceMethod("noOfSites",
signature(object="parameterOptions",
value="numeric"),
function(object,value){
object@noOfSites<-value
return(object)
}
)
setReplaceMethod("noOfSites",
signature(object="parameterOptions",
value="character"),
function(object,value){
object@noOfSites<-value
return(object)
}
)
setMethod("PWMpseudocount","parameterOptions",
function(object) object@PWMpseudocount
)
setReplaceMethod("PWMpseudocount",
signature(object="parameterOptions",
value="numeric"),
function(object, value){
object@PWMpseudocount<-value
return(object)
}
)
setMethod("ploidy","parameterOptions",
function(object) object@ploidy
)
setReplaceMethod("ploidy",
signature(object="parameterOptions",
value="numeric"),
function(object, value){
object@ploidy<-value
return(object)
}
)
setMethod("boundMolecules","parameterOptions",
function(object) object@boundMolecules
)
setReplaceMethod("boundMolecules",
signature(object="parameterOptions",
value="vector"),
function(object, value){
object@boundMolecules<-value
return(object)
}
)
setMethod("maxSignal","parameterOptions",
function(object) object@maxSignal
)
setReplaceMethod("maxSignal",
signature(object="parameterOptions",
value="numeric"),
function(object, value){
object@maxSignal<-value
return(object)
}
)
setMethod("backgroundSignal","parameterOptions",
function(object) object@backgroundSignal
)
setReplaceMethod("backgroundSignal",
signature(object="parameterOptions",
value="numeric"),
function(object, value){
object@backgroundSignal<-value
return(object)
}
)
setMethod("chipMean","parameterOptions",
function(object) object@chipMean
)
setReplaceMethod("chipMean",
signature(object="parameterOptions",
value="numeric"),
function(object, value){
object@chipMean<-value
return(object)
}
)
setMethod("chipSd","parameterOptions",
function(object) object@chipSd
)
setReplaceMethod("chipSd",
signature(object="parameterOptions",
value="numeric"),
function(object, value){
object@chipSd<-value
return(object)
}
)
setMethod("chipSmooth","parameterOptions",
function(object) object@chipSmooth
)
setReplaceMethod("chipSmooth",
signature(object="parameterOptions",
value="vector"),
function(object, value){
object@chipSmooth<-value
return(object)
}
)
setMethod("removeBackground","parameterOptions",
function(object) object@removeBackground
)
setReplaceMethod("removeBackground",
signature(object="parameterOptions",
value="vector"),
function(object, value){
object@removeBackground<-value
return(object)
}
)
setMethod(".ZeroBackground","parameterOptions",
function(object) object@ZeroBackground
)
setReplaceMethod(".ZeroBackground",
signature(object="parameterOptions",
value="vector"),
function(object, value){
object@ZeroBackground<-value
return(object)
}
)
setMethod("stepSize","parameterOptions",
function(object) object@stepSize
)
setReplaceMethod("stepSize",
signature(object="parameterOptions",
value="numeric"),
function(object, value){
object@stepSize<-value
return(object)
}
)
setMethod("lociWidth","parameterOptions",
function(object) object@lociWidth
)
setReplaceMethod("lociWidth",
signature(object="parameterOptions",
value="numeric"),
function(object, value){
object@lociWidth<-value
return(object)
}
)
setReplaceMethod("noiseFilter",
signature(object="parameterOptions",
value="character"),
function(object, value){
object@noiseFilter<-value
return(object)
}
)
setMethod("noiseFilter","parameterOptions",
function(object) object@noiseFilter
)
setMethod(".paramTag","parameterOptions",
function(object) object@paramTag
)
setReplaceMethod(".paramTag",
signature(object="parameterOptions",
value="character"),
function(object, value){
object@paramTag<-value
return(object)
}
)
setMethod("loci","ChIPScore",
function(object) object@loci
)
setReplaceMethod(".loci",
signature(object="ChIPScore",
value="loci"),
function(object, value){
object@loci<-value
return(object)
}
)
setMethod("scores","ChIPScore",
function(object) object@scores
)
setReplaceMethod(".scores",
signature(object="ChIPScore",
value="list"),
function(object, value){
object@scores<-value
return(object)
}
)
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