Description Usage Arguments Details Author(s)
View source: R/apt_cytoscan_process.R
This function performs the normalization of a CEL file of Affymetrix CytoScanHD_Array microarray using the APT binary (apt-copynumber-cyto).
1 2 3 4 5 6 7 | CS.Process(CEL = NULL, samplename = NULL, dual.norm = FALSE,
normal.diploid = FALSE, l2r.level = "weighted", gc.renorm = TRUE,
gc.rda = NULL, wave.renorm = TRUE, wave.rda = NULL,
mingap = 1E+06, out.dir = getwd(), oschp.keep = FALSE, force.OS =
NULL, apt.version = "2.4.0", apt.build = "na33.r4", genome.pkg =
"BSgenome.Hsapiens.UCSC.hg19", return.data = FALSE, write.data =
TRUE, plot = TRUE, force = FALSE)
|
CEL |
A CEL file. |
samplename |
Name of the analyzed sample. |
dual.norm |
Perform a dual-channel normalization (recommended for a better wave-effect bias normalization). |
normal.diploid |
Consider the sample as normal-diploid (not recommended for tumors). |
l2r.level |
Type of log2(ratio) to extract : |
gc.renorm |
Perform a 'GC-content' re-normalization after APT processing. |
gc.rda |
If |
wave.renorm |
Perform a 'Wave-effect' re-normalization after APT processing. |
wave.rda |
If |
mingap |
Minimum genomic size to be considered as an uncovered gap in the design (allows to discard centromeres). |
out.dir |
The path to output results. |
oschp.keep |
Keep the intermediate OSCHP (HDF5) file. |
force.OS |
Specifiy the OS type of the execution machine (see Details). |
apt.version |
Version of the APT tool |
apt.build |
Affymetrix genome build version. |
genome.pkg |
The name of an installed |
return.data |
Return data when finished. |
write.data |
Write the results as a RDS file. |
plot |
Perform plots. |
force |
If some result files already exist, delete them before runing. |
force.OS
is NULL
by default, but can take any of these values :
linux
windows
osx
Bastien Job
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