Compute pathway enrichment scores while accounting for term-term relations. This package uses a regularized multiple linear regression to regress differential expression p-values obtained from multi-condition experiments on a pathway membership matrix. By doing so, it is able to incorporate additional biological knowledge into the enrichment analysis and to estimate pathway enrichment scores more robustly.
Package details |
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Bioconductor views | DifferentialExpression GeneExpression GraphAndNetwork Network NetworkEnrichment Regression Software StatisticalMethod |
Maintainer | |
License | GPL-3 |
Version | 1.5.1 |
URL | https://github.com/cbg-ethz/pareg |
Package repository | View on GitHub |
Installation |
Install the latest version of this package by entering the following in R:
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