cbg-ethz/pareg: Pathway enrichment using a regularized regression approach

Compute pathway enrichment scores while accounting for term-term relations. This package uses a regularized multiple linear regression to regress differential expression p-values obtained from multi-condition experiments on a pathway membership matrix. By doing so, it is able to incorporate additional biological knowledge into the enrichment analysis and to estimate pathway enrichment scores more robustly.

Getting started

Package details

Bioconductor views DifferentialExpression GeneExpression GraphAndNetwork Network NetworkEnrichment Regression Software StatisticalMethod
Maintainer
LicenseGPL-3
Version1.5.1
URL https://github.com/cbg-ethz/pareg
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("cbg-ethz/pareg")
cbg-ethz/pareg documentation built on July 20, 2023, 7:30 p.m.