.getABMLE | R Documentation |
Wrapper function to derive MLE estimates of a, b from beads-only samples
.getABMLE( object, prop.offset = 1e-08, optim.method = "default", lower = 1, upper = Inf )
object |
a |
prop.offset |
offset to use when the proportion of reads is 0. |
optim.method |
optimization method passed to |
lower |
lower bound for the shape parameters. |
upper |
upper bound for the shape parameters. |
a data frame of MLE estimates of a, b
[stats::optim]
for available optimization methods
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