scDatExSim: Data: Toy example of simulated data

In scDD: Mixture modeling of single-cell RNA-seq data to identify genes with differential distributions

Description

Toy example data in SingleCellExperiment format for 500 genes to illustrate how to generate simulated data from example data using simulateSet. Contains 5 genes from each category (DE, DP, DM, DB, EE, and EP).

Usage

data(scDatExSim)

Format

An object of class SingleCellExperiment containing data for 30 genes for 200 samples (100 from condition 1 and 100 from condition 2). Condition labels (1 or 2) are stored in the colData slot. Row names of the assayData slot contain the two letter category label that the gene was simulated from (e.g. 'EE', 'DB', ...) along with the row number (1-30).

Value

An RData object, see Format section for details

References

Korthauer KD, Chu LF, Newton MA, Li Y, Thomson J, Stewart R, Kendziorski C. A statistical approach for identifying differential distributions in single-cell RNA-seq experiments. Genome Biology. 2016 Oct 25;17(1):222. https://genomebiology.biomedcentral.com/articles/10.1186/s13059-016-1077-y

Examples

# load toy example of simulated data
data(scDatExSim)

scDD documentation built on Nov. 8, 2020, 7:10 p.m.