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Account for missing values in label-free mass spectrometry data without imputation. The package implements a probabilistic dropout model that ensures that the information from observed and missing values are properly combined. It adds empirical Bayesian priors to increase power to detect differentially abundant proteins.
Package details |
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Author | Constantin Ahlmann-Eltze [aut, cre] (<https://orcid.org/0000-0002-3762-068X>), Simon Anders [ths] (<https://orcid.org/0000-0003-4868-1805>) |
Bioconductor views | Bayesian DifferentialExpression MassSpectrometry Normalization Proteomics QualityControl Regression Software |
Maintainer | Constantin Ahlmann-Eltze <artjom31415@googlemail.com> |
License | GPL-3 |
Version | 1.4.0 |
URL | https://github.com/const-ae/proDA |
Package repository | View on Bioconductor |
Installation |
Install the latest version of this package by entering the following in R:
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