app: Processed scRNAseq from pooled CRISPR screens

In mnem: Mixture Nested Effects Models

Description

Example data: mnem results for the Dixit et al., 2016 and Datlinger et al., pooled CRISPR screens. For details see the vignette or function createApp().

Usage

app

References

Datlinger, P., Rendeiro, A., Schmidl, C., Krausgruber, T., Traxler, P., Klughammer, J., Schuster, L. C., Kuchler, A., Alpar, D., and Bock, C. (2017). Pooled crispr screening with single-cell transcriptome readout. Nature Methods, 14, 297-301.

Dixit, A., Parnas, O., Li, B., Chen, J., Fulco, C. P., Jerby-Arnon, L., Marjanovic, N. D., Dionne, D., Burks, T., Raychowdhury, R., Adamson, B., Norman, T. M., Lander, E. S., Weissman, J. S., Friedman, N., and Regev, A. (2016). Perturb-seq: Dissecting molecular circuits with scalable single-cell rna profiling of pooled genetic screens. Cell, 167(7), 1853-1866.e17.

Examples

data(app)

mnem documentation built on Nov. 18, 2020, 2 a.m.