The poolScreenExp
class is an S4 class used to store
sgRNA and gene related data as well as parameters necessary
for statistical model.
sgRNAData
A SummarizedExperiment containing the data related to sgRNAs.
FittingIntervals
A vector defining the limits of the intervals used for fitting of null model.
LFCModelParameters
A vector of parameters estimated when fitting the null model.
GeneData
SummarizedExperiment containing the data related to genes.
FittingOptions
A named list with options for fitting: IntervalFraction - fraction of sgRNAs used in every fitting interval (default 0.1), alphaCutoff - alpha cutoff for alpha RRA algorithm (default: 0.05).
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