Nothing
## ----echo=FALSE, include=FALSE------------------------------------------------
knitr::opts_chunk$set(tidy = FALSE, cache = TRUE, dev = "png",
message = FALSE, error = FALSE, warning = TRUE)
## -----------------------------------------------------------------------------
library("SummarizedBenchmark")
library("magrittr")
## -----------------------------------------------------------------------------
data(tdat)
## -----------------------------------------------------------------------------
head(tdat)
## -----------------------------------------------------------------------------
adj_bonf <- p.adjust(p = tdat$pval, method = "bonferroni")
adj_bh <- p.adjust(p = tdat$pval, method = "BH")
qv <- qvalue::qvalue(p = tdat$pval)
adj_qv <- qv$qvalues
## -----------------------------------------------------------------------------
adj <- cbind.data.frame(adj_bonf, adj_bh, adj_qv)
head(adj)
## -----------------------------------------------------------------------------
b <- BenchDesign(data = tdat)
## -----------------------------------------------------------------------------
b <- addMethod(bd = b, label = "bonf", func = p.adjust,
params = rlang::quos(p = pval, method = "bonferroni"))
## -----------------------------------------------------------------------------
b <- b %>%
addMethod(label = "BH",
func = p.adjust,
params = rlang::quos(p = pval, method = "BH")) %>%
addMethod(label = "qv",
func = qvalue::qvalue,
params = rlang::quos(p = pval),
post = function(x) { x$qvalues })
## -----------------------------------------------------------------------------
b
## -----------------------------------------------------------------------------
printMethods(b)
## -----------------------------------------------------------------------------
sb <- buildBench(b, truthCols = "H")
## -----------------------------------------------------------------------------
head(assay(sb))
## -----------------------------------------------------------------------------
colData(sb)
## -----------------------------------------------------------------------------
rowData(sb)
## ----addPerformanceMetric-----------------------------------------------------
sb <- addPerformanceMetric(
object = sb,
assay = "H",
evalMetric = "TPR",
evalFunction = function(query, truth, alpha = 0.1) {
goodHits <- sum((query < alpha) & truth == 1)
goodHits / sum(truth == 1)
}
)
performanceMetrics(sb)[["H"]]
## -----------------------------------------------------------------------------
resWide <- estimatePerformanceMetrics(sb, alpha = c(0.05, 0.1, 0.2))
resWide
## ----elWide-------------------------------------------------------------------
elementMetadata(resWide)
## -----------------------------------------------------------------------------
sb <- estimatePerformanceMetrics(sb,
alpha = c(0.05, 0.1, 0.2),
addColData = TRUE)
colData(sb)
elementMetadata(colData(sb))
## -----------------------------------------------------------------------------
estimatePerformanceMetrics(sb,
alpha = c(0.05, 0.1, 0.2),
tidy = TRUE)
## -----------------------------------------------------------------------------
head(tidyUpMetrics(sb))
## -----------------------------------------------------------------------------
tidyUpMetrics(sb) %>%
dplyr:::filter(label == "bonf", alpha == 0.1, performanceMetric == "TPR") %>%
dplyr:::select(value)
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