Nothing
## ----style, include=FALSE, results='hide'-------------------------------------
BiocStyle::markdown()
library(boot)
library(fission)
library(SummarizedExperiment)
library(ROCpAI)
## ----installation, eval=FALSE-------------------------------------------------
# devtools::install_github("juanpegarcia/ROCpAI")
## ---- echo=FALSE, include=FALSE, results='hide'-------------------------------
data("fission")
genes <- as.data.frame(cbind(strain <- colData(fission)$strain, t(assay(fission)[c("SPNCRNA.1080","SPAC186.08c","SPNCRNA.1420","SPCC70.08c","SPAC212.04c"),])))
colnames(genes) <- c("Strain", "Gene1", "Gene2", "Gene3", "Gene4", "Gene5" )
## -----------------------------------------------------------------------------
genes
## -----------------------------------------------------------------------------
pointsCurve(genes[,1], genes[,2])
## -----------------------------------------------------------------------------
resultMc <- mcpAUC(genes, low.value = 0, up.value = 0.25, plot=TRUE)
resultMc
## -----------------------------------------------------------------------------
test.Mc<- assay(resultMc)
test.Mc$St_pAUC
## -----------------------------------------------------------------------------
test.Mc$pAUC
## -----------------------------------------------------------------------------
resultsT <- tpAUC(genes, low.value = 0, up.value = 0.25, plot=TRUE)
resultsT
## -----------------------------------------------------------------------------
test.tpAUC <- assay(resultsT)
## -----------------------------------------------------------------------------
test.tpAUC$St_pAUC
## -----------------------------------------------------------------------------
test.tpAUC$pAUC
## ---- warning='hide'----------------------------------------------------------
resultstboot<- tpAUCboot(genes,low.value = 0, up.value = 0.25)
## ---- echo='hide'-------------------------------------------------------------
test.tpAUCboot <- assay(resultstboot)
resultT <- t(as.data.frame(cbind(test.tpAUCboot$Tp_AUC,test.tpAUCboot$sd,test.tpAUCboot$lwr,test.tpAUCboot$upr)))
colnames(resultT) <- c("Gene1", "Gene2", "Gene3", "Gene4", "Gene5")
rownames(resultT) <- c("Tp_AUC","sd","lwr","upr")
## -----------------------------------------------------------------------------
resultT
## ---- warning='hide'----------------------------------------------------------
resultsMcboot <- mcpAUCboot(genes,low.value = 0, up.value = 0.25)
## ---- echo='hide', results='hide'---------------------------------------------
test.mcpAUCboot <- assay(resultsMcboot)
resultMc <- t(as.data.frame(cbind(test.mcpAUCboot$MCp_AUC,test.mcpAUCboot$sd,test.mcpAUCboot$lwr,test.mcpAUCboot$upr)))
colnames(resultMc) <- c("Gene1", "Gene2", "Gene3", "Gene4", "Gene5")
rownames(resultMc) <- c("MCp_AUC","sd","lwr","upr")
## -----------------------------------------------------------------------------
resultMc
## ----sessionInfo, eval=TRUE---------------------------------------------------
sessionInfo()
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