bcMigsaRes: A MIGSA results object obtained from breast cancer data

In MIGSA: Massive and Integrative Gene Set Analysis

Description

A MIGSA results object (MIGSAres) obtained using the datasets:

• mainz (microarray).

• nki (microarray).

• tcga (microarray).

• tcga (RNAseq).

• transbig (microarray).

• unt (microarray).

• upp (microarray).

• vdx (microarray).

Each dataset subjects were classified using the PAM50 algorithm. For this analysis only Basal and Luminal A subjects were kept (this was the contrast used, i.e., Basal vs. LumA).

Format

A MIGSAres object.

Details

Datasets were tested for gene set enrichment over:

• the org.Hs.eg.db Gene Ontology gene sets, resulting in 14,291 as BP, 1,692 CC and 4,263 MF.

• KEGG gene sets downloaded from enrichr database resulting in 179 gene sets.

NOTE: For package space purposes, this bcMigsaRes object contains only the first 200 gene sets (subsetted from total result). For fully described information and a step-by-step guide in how this object was generated, please refer to MIGSA's Vignette. Full bcMigsaRes object results can be downloaded (refer to Vignette).

MIGSA documentation built on Nov. 8, 2020, 8:26 p.m.