#' @export
#' @name fitGAM
#' @title fitGAM
#' @param ... parameters including:
setGeneric(
name = "fitGAM",
signature = 'counts',
def = function(counts, ...) {
standardGeneric("fitGAM")
}
)
#' @export
#' @title Perform statistical test to check for DE between final stages of every
#' lineage.
#' @name diffEndTest
#' @param ... parameters including:
setGeneric(
name = "diffEndTest",
#signature = 'models',
def = function(models, ...) {
standardGeneric("diffEndTest")
}
)
#' @export
#' @title Perform statistical test to check for DE between starting point and the end
#' stages of every lineage
#' @name startVsEndTest
#' @param ... parameters including:
setGeneric(
name = "startVsEndTest",
#signature = 'models',
def = function(models, ...) {
standardGeneric("startVsEndTest")
}
)
#' @export
#' @title Perform test of early differences between lineages
#' @name earlyDETest
#' @param ... parameters including:
setGeneric(
name = "earlyDETest",
#signature = 'models',
def = function(models, ...) {
standardGeneric("earlyDETest")
}
)
#' @export
#' @title Assess differential expression pattern between lineages.
#' @name patternTest
#' @param ... parameters including:
setGeneric(
name = "patternTest",
#signature = 'models',
def = function(models, ...) {
standardGeneric("patternTest")
}
)
#' @export
#' @name associationTest
#' @title Perform statistical test to check whether gene expression is constant across
#' pseudotime within a lineage
#' @param ... parameters including:
setGeneric(
name = "associationTest",
#signature = 'models',
def = function(models, ...) {
standardGeneric("associationTest")
}
)
#' @export
setGeneric(
name = "clusterExpressionPatterns",
#signature = 'models',
def = function(models, ...) {
standardGeneric("clusterExpressionPatterns")
}
)
#' @export
#' @rdname evaluateK
#' @title Evaluate the optimal number of knots required for fitGAM.
#' @param ... parameters including:
setGeneric(
name = "evaluateK",
signature = 'counts',
def = function(counts, ...) {
standardGeneric("evaluateK")
}
)
#' @export
#' @title Plot the log-transformed counts and the fitted values for a particular
#' gene along all lineages
#' @name plotSmoothers
#' @param ... parameters including:
setGeneric(
name = "plotSmoothers",
#signature = 'counts',
def = function(models, ...) {
standardGeneric("plotSmoothers")
}
)
#' @export
#' @title Plot gene expression in reduced dimension.
#' @description Plot the gene in reduced dimensional space.
#' @name plotGeneCount
#' @param ... parameters including:
setGeneric(
name = "plotGeneCount",
#signature = 'curve',
def = function(curve, ...) {
standardGeneric("plotGeneCount")
}
)
#' @export
#' @title Assess differential expression patterns between conditions
#' within a lineage.
#' @name conditionTest
#' @param ... parameters including:
setGeneric(
name = "conditionTest",
#signature = 'models',
def = function(models, ...) {
standardGeneric("conditionTest")
})
#' @export
#' @name predictSmooth
#' @title predictSmooth
#' @param ... parameters including:
setGeneric(
name = "predictSmooth",
signature = 'models',
def = function(models, ...) {
standardGeneric("predictSmooth")
}
)
#' @export
#' @name predictCells
#' @title predictCells
#' @param ... parameters including:
setGeneric(
name = "predictCells",
signature = 'models',
def = function(models, ...) {
standardGeneric("predictCells")
}
)
#' @export
#' @name nknots
#' @title knots
#' @param ... parameters including:
setGeneric(
name = "nknots",
signature = 'models',
def = function(models, ...) {
standardGeneric("nknots")
}
)
#' @export
#' @title Get expression peak cascade of genes along a lineage.
#' @name cascade
#' @param ... parameters including:
setGeneric(
name = "cascade",
signature = 'models',
def = function(models, ...) {
standardGeneric("cascade")
}
)
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