This package generates pathway scores from expression data for single samples after training on a reference cohort. The score is generated by taking the expression of a gene set (pathway) from a reference cohort and performing linear discriminant analysis to distinguish samples in the cohort that have the pathway augmented and not. The separating hyperplane is then used to score new samples.
Package details |
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Author | Natalie R. Davidson |
Bioconductor views | BiomedicalInformatics Classification DimensionReduction GeneExpression Pathways RNASeq Software Transcriptomics |
Maintainer | Natalie R. Davidson <natalie.davidson@inf.ethz.ch> |
License | MIT + file LICENSE |
Version | 0.99.15 |
Package repository | View on GitHub |
Installation |
Install the latest version of this package by entering the following in R:
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