isarnassiri/CMEA: CMEA: An R package for Systematic Exploration of Single-Cell Morphological Phenotypes from Transcriptomic Profile
CMEA is a tool for cell morphology enrichment analysis and link transcriptomic alterations with cell morphological phenotypes. In our approach we (1) map the transcriptomic profile of a query against the L1000 LINCS repository, (2) create a gene set repository for cell morphological features (CM), (3) identify the top CMs associated with alterations and analyze their direction of regulation, and (4) model a regulatory network of cell morphological phenotypes.
Getting started
Browse package contents
Package details |
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| Author | Isar Nassiri, Matthew McCall |
| Bioconductor views | Regression Software StatisticalMethod |
| Maintainer | Isar Nassiri <isar.nassiri@oncology.ox.ac.uk> |
| License | GPL-2 |
| Version | 0.99.64 |
| Package repository | View on GitHub |
| Installation |
Install the latest version of this package by entering the following in R:
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