keep in ggs object the design "i,e eg (1,0,1,1)" and the spline templates matrices "ie, eg (X0, X1)". when computng spline errors i) do not rextract those and ii) compute directly the spline standard errors just once using and then put them back into the returned object by replicating values. You will gain a factor 4 on experiment with duplicates and much more if we apply it for large datasets (say groups of 100 vs 100 patients).
add logging in parallel computation (see vignette on BiocParallel: Logging)
set #define ARMA_64BIT_WORD or check if it is set and throw warning that matrices should not exceed certain size.
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