compbiomed/ASSIGN: Adaptive Signature Selection and InteGratioN (ASSIGN)
ASSIGN is a computational tool to evaluate the pathway deregulation/activation status in individual patient samples. ASSIGN employs a flexible Bayesian factor analysis approach that adapts predetermined pathway signatures derived either from knowledge-based literature or from perturbation experiments to the cell-/tissue-specific pathway signatures. The deregulation/activation level of each context-specific pathway is quantified to a score, which represents the extent to which a patient sample encompasses the pathway deregulation/activation signature.
Getting started
Browse package contents
Package details |
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| Author | Ying Shen, Andrea H. Bild, W. Evan Johnson, and Mumtehena Rahman |
| Bioconductor views | Bayesian GeneExpression Pathways Software |
| Maintainer | Ying Shen <yshen3@bu.edu>, W. Evan Johnson <wej@bu.edu>, David Jenkins <dfj@bu.edu>, Mumtehena Rahman <moom.rahman@utah.edu> |
| License | MIT + file LICENSE |
| Version | 1.37.0 |
| URL | https://compbiomed.github.io/ASSIGN/ |
| Package repository | View on GitHub |
| Installation |
Install the latest version of this package by entering the following in R:
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