charles-plessy/clonotypeR.old: High throughput analysis of T cell antigen receptor sequences

High throughput analysis of T cell antigen receptor sequences The genes encoding T cell receptors are created by somatic recombination, generating an immense combination of V, (D) and J segments. Additional processes during the recombination create extra sequence diversity between the V an J segments. Collectively, this hyper-variable region is called the CDR3 loop.

The purpose of this package is to process and quantitatively analyse millions of V-CDR3-J combination, called clonotypes, from multiple sequence libraries.

install.packages("remotes")
remotes::install_github("charles-plessy/clonotypeR.old")