Interactively analyses Intron Retention and Alternative Splicing Events (ASE) in RNA-seq data. NxtIRF quantifies ASE events in BAM files aligned to the genome using a splice-aware aligner such as STAR. The core quantitation algorithm relies on the IRFinder/C++ engine ported via Rcpp for multi-platform compatibility. In addition, NxtIRF provides convenient pipelines for downstream analysis and publication-ready visualisation tools. Note that NxtIRFcore is now replaced by SpliceWiz in Bioconductor 3.16 onwards.
Package details |
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Bioconductor views | AlternativeSplicing Coverage DifferentialSplicing RNASeq Software Transcriptomics |
Maintainer | |
License | MIT + file LICENSE |
Version | 1.3.2 |
URL | https://github.com/alexchwong/NxtIRFcore |
Package repository | View on GitHub |
Installation |
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